Pulmonary Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India.
Pathology & Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, India.
BMJ Case Rep. 2022 Feb 25;15(2):e246683. doi: 10.1136/bcr-2021-246683.
Primary pleural liposarcoma (PPL) is a rare primary malignant pleural tumour originating from primitive mesenchymal tissue. We report the case of a 25-year-old man with a 6-week history of shortness of breath, cough, chest pain and hoarseness of voice. Chest X-ray showed a left opacified hemithorax, and thoracic CT scan revealed a large, heterogeneous, hypodense mass in the left hemithorax. The patient was taken up for ultrasound-guided core biopsy of the mass lesion, and histopathological examination revealed the diagnosis as a pleomorphic variant of PPL. We highlight the importance of considering PPL as a differential diagnosis in cases of large hemithoracic masses.
原发性胸膜脂肪肉瘤（PPL）是一种罕见的原发于原始间叶组织的恶性胸膜肿瘤。我们报告了 1 例 25 岁男性患者，其病史为 6 周的呼吸困难、咳嗽、胸痛和声音嘶哑。胸部 X 线片显示左侧胸腔不透明，胸部 CT 扫描显示左侧胸腔内有一个大的、异质性、低密 度肿块。患者行超声引导下肿块病变的核心活检，组织病理学检查显示诊断为多形性 PPL 变异型。我们强调了在大 胸腔肿块的病例中，将 PPL 作为鉴别诊断的重要性。
