Department of Surgery, NorthShore University HealthSystem, 2650 Ridge Ave, GCSI Suite B665, Evanston, IL, 60201, USA.
Department of Surgery, University of Chicago, Chicago, USA.
World J Surg. 2022 Jul;46(7):1542-1546. doi: 10.1007/s00268-022-06477-1. Epub 2022 Feb 25.
Peroral endoscopic myotomy (POEM) utilizes the principles of natural orifice transluminal surgery to create an operative tunnel within the submucosal space, perform an endoluminal esophagogastromyotomy, and ultimately mitigate the progressive symptoms of achalasia. POEM is an innovative minimally invasive technique increasing in popularity and clinical significance as an effective treatment for achalasia and other disorders of spastic esophageal motility.
A comprehensive literature review was performed regarding the procedure, outcomes, and technical advancements in POEM.
A growing number of studies world-wide have shown that POEM is a safe and effective for all types of achalasia, sigmoid and non-sigmoid type.
POEM continues to gain traction as a highly effective therapeutic modality for achalasia. As natural orifice transluminal surgery advances, further research is necessary to optimize utilization of endoluminal functional imaging, to tailor endoscopic technique, and to address the adverse effect of post-operative reflux and esophagitis.
经口内镜下肌切开术（POEM）利用经自然腔道内镜手术的原理，在黏膜下层创建一个手术隧道，进行内镜下食管胃切开术，最终减轻贲门失弛缓症的进行性症状。POEM 是一种创新的微创技术，作为贲门失弛缓症和其他痉挛性食管动力障碍的有效治疗方法，其在临床应用中的重要性和普及程度不断增加。
对 POEM 的手术过程、结果和技术进展进行了全面的文献回顾。
世界范围内越来越多的研究表明，POEM 是治疗所有类型贲门失弛缓症（包括矢状型和非矢状型）的一种安全有效的方法。
POEM 作为治疗贲门失弛缓症的一种非常有效的治疗方法，其应用不断增加。随着经自然腔道内镜手术的发展，有必要进一步研究如何优化使用腔内功能成像、调整内镜技术，并解决术后反流和食管炎的不良影响。
