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[Ketamine--a suitable agent for emergency situations (author's transl)].

作者信息

Rust M, Landauer B, Kolb E

出版信息

Anaesthesist. 1978 May;27(5):205-12.

PMID:352188
Abstract

Various surgical procedures have been performed using ketamine alone (Group I) or ketamine-relaxant-air anaesthesia (Group II). In all patients we observed a significant rise in systolic and diastolic blood pressure and pulse rate. The intraoperative values showed a tendency to return to normal. Ten minutes after injection 2 mg/kg body-weight i.v., ketamine caused a significant reduction in arterial PO2 and oxygen saturation as well as a significant rise in arterial PCO2, though these changes were of no clinical importance. In both groups the intraoperative values were normal as compared to the preoperative level. In all cases base excess reflecting the metabolic side of blood gas analysis was within normal range. Based on our findings we recommend the use of ketamine as a sole anesthetic agent for IPPB ventilated as well as spontaneously breathing patients in disaster situations.

摘要

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引用本文的文献

1
Influence of ketamine on catecholamine secretion in the perfused rat adrenal medulla.氯胺酮对灌流大鼠肾上腺髓质儿茶酚胺分泌的影响。
Korean J Physiol Pharmacol. 2008 Jun;12(3):101-9. doi: 10.4196/kjpp.2008.12.3.101. Epub 2008 Jun 30.
2
Use of ketamine in prolonged entrapment.氯胺酮在长时间被困情况中的应用。
J Accid Emerg Med. 1994 Sep;11(3):189-91. doi: 10.1136/emj.11.3.189.
3
Cardiovascular and respiratory effects of ketamine in the neonatal lamb.
Can Anaesth Soc J. 1986 Jan;33(1):10-5. doi: 10.1007/BF03010902.
4
Sympathoneuronal and sympathoadrenal activation during ketamine anesthesia.
Eur J Clin Pharmacol. 1979 Sep;16(2):91-5. doi: 10.1007/BF00563113.