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使用自体腘绳肌腱混合移植物对一名患有活动度过高型埃勒斯-当洛综合征患者进行双束前交叉韧带重建:病例报告

Double-bundle anterior cruciate ligament reconstruction using autologous hamstring tendon hybrid grafts in a patient with hypermobile Ehlers-Danlos Syndrome: A case report.

作者信息

Hishimura Ryosuke, Kondo Eiji, Matsuoka Masatake, Iwasaki Koji, Kawaguchi Yasuyuki, Suzuki Yuki, Onodera Tomohiro, Momma Daisuke, Iwasaki Norimasa

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, Hokkaido 060-8638, Japan.

Centre for Sports Medicine, Hokkaido University Hospital, North 14 West 5, Kita-ku, Sapporo, Hokkaido 060-8648, Japan.

出版信息

Knee. 2022 Mar;35:81-86. doi: 10.1016/j.knee.2022.02.005. Epub 2022 Feb 24.

DOI:10.1016/j.knee.2022.02.005
PMID:35220136
Abstract

BACKGROUND

Ehlers-Danlos syndrome (EDS) is a connective tissue disorder characterized by skin hyperextensibility, joint hypermobility, and tissue friability. Hypermobile type Ehlers-Danlos syndrome (hEDS) is considered one of the EDS subtypes characterized by generalized joint hypermobility. Although there have been a few case reports which described surgical considerations for anterior cruciate ligament (ACL) reconstructions in patients with other types of EDS, no reports have described those in patients with hEDS.

CASE PRESENTATION

We report a case of ACL injury in an 18-year-old male patient with hEDS. The patient was successfully treated with an anatomic double-bundle ACL reconstruction using autologous hamstring tendon hybrid grafts which consist of hamstring tendons connected in a series with commercially available polyester tape. The autogenous tendon portion of the anteromedial and posterolateral bundles were composed of 4 and 2 strands of hamstring tendons, respectively. After 2 weeks of knee joint immobilization, continuous passive motion exercise of the knee joint and partial weight-bearing was allowed. A hinged knee brace was used for a period of 5 months postoperatively. Second-look arthroscopy at 30 months showed that the ACL graft had no laceration and an excellent coverage of the synovium. At 36 months after surgery, the side-to-side differences in the anterior laxity was remarkably improved. The operated knee showed negative Lachman test and had a full range of motion.

CONCLUSIONS

To the best of our knowledge, this represents the first report of anatomic double-bundle ACL reconstruction in patients with hEDS and demonstrates excellent clinical and functional outcomes.

摘要

背景

埃勒斯-当洛综合征(EDS)是一种结缔组织疾病,其特征为皮肤过度伸展、关节活动过度和组织脆弱。活动过度型埃勒斯-当洛综合征(hEDS)被认为是EDS的亚型之一,其特征为全身性关节活动过度。尽管已有一些病例报告描述了其他类型EDS患者前交叉韧带(ACL)重建的手术考量,但尚无关于hEDS患者的相关报告。

病例报告

我们报告一例18岁男性hEDS患者的ACL损伤病例。该患者采用自体腘绳肌腱混合移植物成功进行了解剖双束ACL重建,该移植物由腘绳肌腱与市售聚酯带串联而成。前后内侧束和后外侧束的自体肌腱部分分别由4股和2股腘绳肌腱组成。膝关节固定2周后,允许进行膝关节持续被动运动锻炼和部分负重。术后使用铰链式膝关节支具5个月。30个月时的二次关节镜检查显示,ACL移植物无撕裂,滑膜覆盖良好。术后36个月,前向松弛度的左右差异显著改善。手术侧膝关节Lachman试验为阴性,活动范围正常。

结论

据我们所知,这是首例关于hEDS患者解剖双束ACL重建的报告,显示出优异的临床和功能结果。

相似文献

1
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Int Orthop. 2025 Aug 7. doi: 10.1007/s00264-025-06632-y.
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Curr Rev Musculoskelet Med. 2025 May 21. doi: 10.1007/s12178-025-09979-2.
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Regulation of Joint Tissues and Joint Function: Is There Potential for Lessons to Be Learned Regarding Regulatory Control from Joint Hypermobility Syndromes?
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