Mandard A M, Herlin P, Elie H, Juret P
Ann Anat Pathol (Paris). 1978;23(1):63-80.
An optical and ultrastructural study was performed on biopsy and autopsy specimens of Stewart Treves syndrome cutaneous tumours and their metatases. Various histological aspects are described: territories presenting typical vascular differentiation, spindle cell "Kaposi type" territories and undifferentiated territories. The ultrastructural study confirmed the angiomatous differentiation of these tumors and revealed a certain number of arguments in favor of blood rather than lymphatic capillary differentiation of the newly formed vessels. Upon completion of this study, it appeared possible to confirm that the Stewart Treves syndrome corresponds to an anatomo-clinical entity whose histological features are very close to those of primitive cutaneous angiosarcomas.
对斯图尔特-特里夫斯综合征皮肤肿瘤及其转移灶的活检和尸检标本进行了光学和超微结构研究。描述了各种组织学特征:呈现典型血管分化的区域、梭形细胞“卡波西型”区域和未分化区域。超微结构研究证实了这些肿瘤的血管瘤样分化,并揭示了一些证据支持新形成的血管是血行性而非淋巴管性毛细血管分化。完成这项研究后,可以确认斯图尔特-特里夫斯综合征对应于一种解剖学-临床实体,其组织学特征与原发性皮肤血管肉瘤非常接近。