Mansour H, Molitch M E
Comput Biol Med. 1986;16(3):215-21. doi: 10.1016/0010-4825(86)90049-1.
A patient rarely has a single, isolated disease. The situation is usually much more complex since the different parts of the human organism and its metabolism interact with each other on multiple levels and follow several feedback patterns. These interactions and feedback patterns become even more complex when the effects of the external environment are considered. When several diseases are present, the first steps in medical diagnosis are to determine whether one of the diseases interacts with ("Censors") or changes the significant symptoms, signs, or results of the laboratory tests of the other diseases. We will try, within this paper, to go beyond the scope of the first generation of Artificial Intelligence systems in medicine to determine the effects of two diseases on each other. One important part of the effect of two diseases on each other is the effect of Censors. In addition, causal reasoning, reasoning by analogy, and learning from precedents are important and necessary for a human-like expert in medicine. Their application to thyroid diseases, with an implemented system, are considered in this paper.
患者很少仅患有一种孤立的疾病。情况通常要复杂得多,因为人体有机体的不同部分及其新陈代谢在多个层面上相互作用,并遵循多种反馈模式。当考虑外部环境的影响时,这些相互作用和反馈模式会变得更加复杂。当存在多种疾病时,医学诊断的首要步骤是确定其中一种疾病是否与其他疾病相互作用(“审查”)或改变其他疾病的显著症状、体征或实验室检查结果。在本文中,我们将尝试超越第一代医学人工智能系统的范畴,以确定两种疾病之间的相互影响。两种疾病相互影响的一个重要部分是审查的影响。此外,因果推理、类比推理和先例学习对于医学领域类似人类专家来说是重要且必要的。本文将探讨它们在一个已实施的系统中应用于甲状腺疾病的情况。