Fratkin J D, Ward M M, Roberts D W, Sullivan M M
Diagn Cytopathol. 1986 Apr-Jun;2(2):126-32. doi: 10.1002/dc.2840020206.
Computerized tomography (CT)-guided stereotactic biopsies of intracranial lesions in 29 patients were analyzed, paying particular attention to the correlation between core biopsies and aspiration smears. Seven percent were nondiagnostic due to sampling error. Discrepancies occurred between core biopsies and aspiration smears in 10% of the cases. In two instances of such discrepancies, cytologic findings on the aspiration smear yielded the diagnosis of metastatic tumor. One patient, with herpetic encephalitis, was diagnosed by electron microscopic review of the core biopsy only. One patient died of an intraoperative hemorrhage, a complication of the fine-needle technique.
对29例颅内病变患者的计算机断层扫描（CT）引导下立体定向活检进行了分析，特别关注了芯针活检与穿刺涂片之间的相关性。7%的病例因取样误差而诊断不明确。10%的病例中芯针活检与穿刺涂片结果存在差异。在其中两例存在差异的病例中，穿刺涂片的细胞学检查结果确诊为转移性肿瘤。仅1例疱疹性脑炎患者通过对芯针活检进行电子显微镜检查确诊。1例患者死于术中出血，这是细针技术的一种并发症。
