左侧尾状核头部卒中前驱期的病理性发笑
Pathological Laughter Prodromal to a Stroke of the Head of the Left Caudate Nucleus.
作者信息
Beth Urhoy Matthew, House William J
机构信息
Department of Medicine, UMass Medical School, Baystate Medical Center, Springfield, Massachusetts, USA.
Neurosciences Division, UMass Medical School, Baystate Medical Center, Springfield, Massachusetts, USA.
出版信息
Case Rep Neurol. 2022 Jan 13;14(1):1-4. doi: 10.1159/000521304. eCollection 2022 Jan-Apr.
A 38-year-old right-handed female with a past history of intermittent painful rash, dizzy spells, and chronic daily headaches as well as episodic migraines experienced an episode of transient involuntary pathological laughter, right arm weakness, and expressive dysphasia. She was found on MRI to have multiple strokes in multiple vascular distributions, including one in the head of the left caudate. A cardiac ECHO found an atrial myxoma, with extensive evaluation for other causes of stroke unrevealing. The differential diagnosis for pathological laughter in this patient is discussed. The most plausible cause in this patient is an infarct to the head of the left caudate nucleus caused by an embolus of the atrial myxoma.
一名38岁右利手女性，既往有间歇性疼痛性皮疹、头晕发作、慢性每日头痛以及发作性偏头痛病史，经历了一次短暂性非自主性病理性发笑、右臂无力和表达性失语发作。MRI检查发现其在多个血管分布区域有多处卒中，包括左侧尾状核头部一处。心脏超声检查发现一个心房黏液瘤，对其他卒中原因进行的广泛评估未发现异常。本文讨论了该患者病理性发笑的鉴别诊断。该患者最可能的病因是心房黏液瘤栓子导致左侧尾状核头部梗死。
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