Mayerhofer Ernst, Kanz Dirk, Avcil Tuba, Taschner Christian, Strecker Christoph, Niesen Wolf-Dirk
Clinic of Neurology and Neurophysiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Case Rep Neurol. 2022 Feb 1;14(1):19-24. doi: 10.1159/000521314. eCollection 2022 Jan-Apr.
Transient global amnesia (TGA) is a self-limiting neurological condition that temporarily affects patients' ability to access and store memories. So far, its etiology is unknown; however, ischemic origin has been discussed in the past. We present the case of a 61-year-old female with clinical appearance of TGA. MRI and duplex scan revealed punctiform and patchy ischemic lesions in both temporal lobes and right vertebral artery dissection, suggesting basilar artery embolism as the underlying cause. Our case report shows that TGA can be a symptom of ischemic lesions in the hippocampus and patients with presentation of additional focal neurologic symptoms or atypical distribution or appearance of the diffusion-weighted image (multiple/patchy) lesions should get ischemic stroke diagnosis and treatment.
短暂性全面性遗忘症(TGA)是一种自限性神经疾病,会暂时影响患者获取和存储记忆的能力。迄今为止,其病因尚不清楚;不过,过去曾探讨过缺血性起源。我们报告一例61岁女性,临床表现为TGA。磁共振成像(MRI)和双功扫描显示双侧颞叶有散在点状和片状缺血性病变以及右侧椎动脉夹层,提示基底动脉栓塞为潜在病因。我们的病例报告表明,TGA可能是海马体缺血性病变的症状,出现额外局灶性神经症状或弥散加权图像(多个/片状)病变分布或表现不典型的患者应接受缺血性中风的诊断和治疗。