乌干达中部一个大型城市结核病项目中不同活动性结核病发现干预措施的比较效果：描述性研究。

Comparative yield of different active TB case finding interventions in a large urban TB project in central Uganda: a descriptive study.

机构信息

The AIDS Support Organization, Kampala, Uganda.

USAID/Defeat TB Project, University Research Co. LLC, Kampala, Uganda.

出版信息

Afr Health Sci. 2021 Sep;21(3):975-984. doi: 10.4314/ahs.v21i3.3.

DOI:10.4314/ahs.v21i3.3

PMID:35222557

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8843286/

Abstract

INTRODUCTION

Systematic screening for TB among patients presenting to care and among high risk populations is recommended to improve TB case finding. We aimed to describe the comparative yield of three TB screening approaches implemented by a large urban TB project in central Uganda.

METHODS

We abstracted data on the screening cascade from 65 health facilities and their surrounding communities (numbers screened, with presumptive TB, receiving a diagnostic test and diagnosed with TB) from the different clinic and community TB registers.

RESULTS

From January 2018 to December 2019, 93,378 (24%) of all patients screened at health facilities had presumptive TB; 77,381 (82.9%) received a diagnostic test and 14,305 (18.5%) were diagnosed with TB. The screening yield (the number of patients diagnosed with TB out of all patients screened) was 0.3% and was three times higher among men than women (0.6% vs 0.2% p<0.01). During targeted community screening interventions, 9874 (21.1%) of all patients screened had presumptive TB; 7034 (71.2%) of these received a diagnostic test and 1699 (24.2%) were diagnosed with TB. The screening yield was higher among men, (3.7% vs 3.3% p<0.01) and highest among children 0-14 (4.8% vs 3.2% p<0.01).

CONCLUSION

Targeted community TB screening interventions improve access to TB diagnosis for men and children 0-14 years.

摘要

简介

系统地对就诊患者和高危人群进行结核病筛查，有助于提高结核病检出率。本研究旨在描述乌干达中部一个大型城市结核病项目实施的三种结核病筛查方法的比较效果。

方法

我们从不同的诊所和社区结核病登记处的 65 个卫生机构及其周边社区的结核病筛查数据库中提取了筛查情况数据（筛查人数、疑似结核病患者人数、接受诊断性检查人数和诊断为结核病人数）。

结果

2018 年 1 月至 2019 年 12 月，在卫生机构接受筛查的所有患者中，有 93378 人（24%）有疑似结核病；77381 人（82.9%）接受了诊断性检查，14305 人（18.5%）被诊断为结核病。筛查检出率（所有筛查患者中诊断为结核病的人数比例）为 0.3%，男性是女性的三倍（0.6%比 0.2%，p<0.01）。在有针对性的社区筛查干预中，所有接受筛查的患者中有 9874 人（21.1%）有疑似结核病；其中 7034 人（71.2%）接受了诊断性检查，1699 人（24.2%）被诊断为结核病。男性的筛查检出率较高（3.7%比 3.3%，p<0.01），0-14 岁儿童的筛查检出率最高（4.8%比 3.2%，p<0.01）。