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小儿食管狭窄:挑战与促进无张力食管吻合的新型手术器械

Pediatric esophageal stenoses: Challenges and new surgical device promoting tension-free esophageal anastomosis.

作者信息

Iozsa Dan Alexandru, Spătaru Radu-Iulian, Tomescu Luminita Florentina, Stiru Ovidiu, Gherghiceanu Florentina, Furtunescu Florentina, Radavoi Daniel, Bacalbasa Nicolae, Balescu Irina, Tulin Adrian

机构信息

Department of Pediatric Surgery, Faculty of Medicine, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Department of Pediatric Surgery, 'Marie S. Curie' Emergency Clinic Hospital for Children, 041451 Bucharest, Romania.

出版信息

Exp Ther Med. 2022 Mar;23(3):220. doi: 10.3892/etm.2022.11144. Epub 2022 Jan 14.

Abstract

Esophageal stenoses of childhood have a broad spectrum of underlying causes. Their treatment is usually minimally invasive by endoscopic means, but sometimes surgery is necessary in refractory cases. Techniques employed in the surgical treatment of esophageal strictures include resection of the stenotic esophageal segment or esophageal substitution procedures. Esophageal anastomosis has always been a challenge in pediatric surgery. Anastomosis complications are linked to anatomical, biological and technical aspects. Mechanical tension between esophageal ends is an important cause of complications including anastomotic leaks or dehiscence. Eleven cases of esophageal stenoses, surgically treated in the Pediatric Surgery Department of Emergency Clinical Hospital for Children 'Marie S. Curie' by a single team in 5 years, were included in the present study. The results showed that, the main causes of esophageal stenosis were represented by corrosive esophageal injury in five cases, complications of esophageal atresia repair in three cases, congenital esophageal stenosis in two cases and chemotherapy-induced esophageal necrosis in acute lymphoblastic leukemia treatment in one case. The authors also designed and presented a device facilitating esophageal anastomosis under tension. Its principle involved temporary absorption of tension at secure points of the two esophageal pouches and reallocating it in equal amounts following anastomosis while decreasing any stretch-related tissue trauma. In conclusion, this auxiliary tool is beneficial for esophageal anastomosis; however, the standard steps of the esophageal anastomosis procedure should still be considered when necessary.

摘要

儿童食管狭窄有多种潜在病因。其治疗通常通过内镜手段进行微创治疗,但在难治性病例中有时需要手术治疗。食管狭窄手术治疗所采用的技术包括狭窄食管段切除术或食管替代手术。食管吻合术一直是小儿外科的一项挑战。吻合术并发症与解剖、生物学和技术方面有关。食管两端之间的机械张力是包括吻合口漏或裂开在内的并发症的重要原因。本研究纳入了5年间在“玛丽·居里”儿童急诊临床医院小儿外科由单一团队手术治疗的11例食管狭窄病例。结果显示,食管狭窄的主要原因包括5例腐蚀性食管损伤、3例食管闭锁修复术后并发症、2例先天性食管狭窄以及1例急性淋巴细胞白血病治疗中化疗引起的食管坏死。作者还设计并展示了一种便于在张力下进行食管吻合的装置。其原理是在两个食管袋的固定点临时吸收张力,并在吻合后将其等量重新分配,同时减少任何与拉伸相关的组织创伤。总之,这种辅助工具对食管吻合有益;然而,必要时仍应考虑食管吻合术的标准步骤。

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