Kimpen J, Bosmans E, Janssen J, Lambrechts J, Van Hoof A, Gielen J, Vandeput H, Van Waes A
Eur J Obstet Gynecol Reprod Biol. 1986 Jun;22(1-2):53-60. doi: 10.1016/0028-2243(86)90089-4.
Ureaplasma urealyticum has been implicated in gynaecological, obstetrical and neonatal pathology. Increased levels of C-reactive protein and total IgM concentrations in cord blood have often been used as a screening method for infectious disease in the fetus and the newborn. Analysis of the isolation rate of U. urealyticum in function of the concentrations of these two parameters in cord blood showed that U. urealyticum was significantly (P less than 0.05) more frequently isolated when CRP was above normal in cord blood. No correlation between the IgM level in the newborn and the presence of U. urealyticum could be established. A significant relationship was found (P less than 0.01) between Ureaplasma isolation in the urine of mother and child on the one hand and gestational age on the other hand, which supports the hypothesis that U. urealyticum may play a role in preterm delivery.
解脲脲原体与妇科、产科及新生儿病理学有关。脐血中C反应蛋白水平升高和总IgM浓度升高常被用作胎儿和新生儿传染病的筛查方法。分析脐血中这两个参数浓度与解脲脲原体分离率的关系表明，当脐血中CRP高于正常水平时，解脲脲原体的分离频率显著更高（P<0.05）。新生儿IgM水平与解脲脲原体的存在之间未发现相关性。一方面，母婴尿液中解脲脲原体的分离与另一方面的孕周之间存在显著关系（P<0.01），这支持了解脲脲原体可能在早产中起作用的假说。
