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增殖性糖尿病视网膜病变视网膜下增殖的临床特征与手术治疗

Clinical Features and Surgical Treatment of Subretinal Proliferation in Proliferative Diabetic Retinopathy.

作者信息

Wu Chan, Dai Rongping, Chen Youxin, Zhang Xiao, Chen Zhe

机构信息

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Key Lab of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

Front Med (Lausanne). 2022 Feb 11;9:833519. doi: 10.3389/fmed.2022.833519. eCollection 2022.

Abstract

PURPOSE

To describe the clinical characteristics, treatments, and prognosis of subretinal proliferation (SRP) in proliferative diabetic retinopathy (PDR) patients.

METHODS

A total of 184 patients (221 eyes) who received vitrectomy for PDR between 2018 and 2021 were retrospectively reviewed. Patients with SRP were further evaluated. The following data were collected from their medical records: demographics, systemic and ophthalmologic findings, and treatment given specifically for SRP. The main outcome measures included the visual acuity (VA), funduscopic examination, and final anatomic success.

RESULTS

Twelve eyes of eleven patients including seven females and four males with a mean age of 47.64 ± 11.21 years were evaluated. The surgical indication for the patients was mainly tractional retinal detachment (TRD) (100.0%). No retinal break was found preoperatively or intraoperatively. Only one eye (8.3%) had undergone subretinal band removal procedure intraoperatively, and the final anatomical success rate was 100%.

CONCLUSION

Subretinal proliferation in PDR was associated with TRD. The retina could reattach successfully after vitrectomy without removal or transection of SRP in most eyes.

摘要

目的

描述增殖性糖尿病视网膜病变(PDR)患者视网膜下增殖(SRP)的临床特征、治疗方法及预后。

方法

回顾性分析2018年至2021年间因PDR接受玻璃体切除术的184例患者(221只眼)。对患有SRP的患者进行进一步评估。从他们的病历中收集以下数据:人口统计学资料、全身和眼科检查结果,以及专门针对SRP的治疗。主要观察指标包括视力(VA)、眼底检查和最终的解剖学成功情况。

结果

对11例患者的12只眼进行了评估,其中女性7例,男性4例,平均年龄47.64±11.21岁。患者的手术指征主要是牵引性视网膜脱离(TRD)(100.0%)。术前或术中均未发现视网膜裂孔。术中仅1只眼(8.3%)进行了视网膜下条索切除术,最终解剖学成功率为100%。

结论

PDR中的视网膜下增殖与TRD相关。在大多数眼中,玻璃体切除术后视网膜可成功复位,无需切除或切断SRP。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/943f/8873153/98f3d728a00d/fmed-09-833519-g0001.jpg

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