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印度南部儿童(0-15 岁)第六神经麻痹的临床特征和处理 - 一项基于医院的研究。

Clinical profile and management of sixth nerve palsy in pediatric patients (0-15 years) in Southern India - A hospital-based study.

机构信息

Department of Paediatric and Strabismus, Aravind Eye Hospital, Pondicherry, India.

Department of Neurophthalmology and Low Vision Services, Aravind Eye Hospital, Pondicherry, India.

出版信息

Indian J Ophthalmol. 2022 Mar;70(3):952-957. doi: 10.4103/ijo.IJO_2211_21.

Abstract

PURPOSE

This study was done to evaluate the clinical profile in pediatric patients (0-16 years) presenting with acute onset esotropia due to sixth nerve palsy and its management options in a tertiary care set up of Southern India.

METHODS

A total of 12 patients presenting to our OPD with acute onset esotropia due to sixth nerve palsies were included in this retrospective study. All patients were observed for 6 months and managed with prism and/or patching while waiting for spontaneous resolution and later managed surgically. Neuroimaging was done in all cases.

RESULTS

The mean deviation of esotropia at presentation was 30.17 ± 5.7 Prism Diopter (range 12-50 Prism Diopter 95% CI, SD 10.11). Mean age of the patients during presentation was 8.6 ± 2.4 years (range: 1-15 years, SD 4.27). Among the common causes of sixth nerve palsy in our study population were trauma and idiopathic intracranial hypertension followed by tumor and miscellaneous causes. Only three patients underwent surgical correction of residual deviation after a waiting period of 6 months for self-resolution. Spontaneous resolution was observed in 41.6% patients, and surgical correction (unilateral resection-recession) was done in 25% of the patients with good surgical outcome.

CONCLUSION

At 1-year follow up, the motor outcome was satisfactory except for one patient who had diffuse pontine glioma and had worsening neurological symptoms on follow-up.

摘要

目的

本研究旨在评估印度南部一家三级护理机构中因第六神经麻痹导致急性内斜视的儿科患者(0-16 岁)的临床特征及其治疗选择。

方法

本回顾性研究共纳入 12 例因第六神经麻痹导致急性内斜视就诊于我院门诊的患者。所有患者均接受了 6 个月的观察,并通过棱镜和/或遮盖治疗,等待自发缓解,随后进行手术治疗。所有患者均进行了神经影像学检查。

结果

斜视的平均偏差在就诊时为 30.17 ± 5.7 棱镜屈光度(范围为 12-50 棱镜屈光度 95%CI,SD 10.11)。就诊时患者的平均年龄为 8.6 ± 2.4 岁(范围:1-15 岁,SD 4.27)。在我们的研究人群中,第六神经麻痹的常见病因是创伤和特发性颅内高压,其次是肿瘤和其他病因。只有 3 例患者在等待 6 个月自行缓解后接受了残余斜视的手术矫正。41.6%的患者出现自发性缓解,25%的患者接受了手术矫正(单侧切除-后退),手术效果良好。

结论

在 1 年的随访中,运动结果令人满意,除了 1 例患有弥漫性桥脑胶质瘤的患者,该患者在随访中出现神经症状恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3452/9114572/887def0bce88/IJO-70-952-g001.jpg

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