Department of Urology, Mayo Clinic Florida, Jacksonville, FL, USA.
Department of Urology, Mayo Clinic Florida, Jacksonville, FL, USA.
J Sex Med. 2022 Apr;19(4):590-593. doi: 10.1016/j.jsxm.2022.01.520. Epub 2022 Feb 26.
Intracavernosal injections (ICI) are a well-established treatment option for men with erectile dysfunction (ED); however, the anticipation of pain with injection remains a significant barrier to the use of ICI.
To evaluate the patient-anticipated degree of pain versus the experienced degree of pain pre- and post-ICI in men undergoing their first injection with an erectile agent.
We studied 51 patients who underwent their first ICI in our men's health clinic. Anticipated needle-associated pain was judged with a pre-injection score, and pain experienced during the injection was judged with a post-injection score. All patients graded their pre- and post-ICI pain using a standard 10-point scale (0-10).
Pre- and post-ICI pain was defined with the visual analogue scale (0-10) in men undergoing their first penile injection.
Medians and interquartile ranges (IQRs) of the patients' age [65 years (54.5-68.0)], pre-injection pain [5 (4-7)], and post-injection pain [1 (1-2)] were recorded. Most men in the study had erectile dysfunction (68.6%) and/or Peyronie's Disease (64.7%). The average pre-injection prediction pain score was 5.45 ± 2.15; the average post-injection perceived pain score was 1.20 ± 0.73. Thus, there was an average discrepancy of over 4 points in predicted pain vs perceived pain. A paired t-test was performed which showed a statistically significant difference between pre- and post-injection scores (P < .05). A Wilcoxson Signed Rank Test showed statistical significance in the difference between pre- and post-injection pain scores (P < .05).
ICI is a safe, effective treatment for patients with ED and is associated with significantly less pain than is anticipated by patients.
STRENGTHS & LIMITATIONS: This is the first report to describe the discrepancy between pre-ICI anticipated pain and post-ICI experienced pain. Limitations include an overall small sample size.
Patients experience significantly less pain with ICI than they anticipate having. This represents an important factor to consider when counseling patients about available ED treatments. Baird B, Wajswol E, Ericson C et al. Pre- and Post-Injection Needle Pain in Patients Undergoing First Intracavernosal Injection. J Sex Med 2022;19:590-593.
阴茎海绵体内注射（ICI）是治疗勃起功能障碍（ED）患者的一种成熟的治疗选择；然而，注射带来的疼痛预期仍然是患者接受 ICI 治疗的一个重要障碍。
评估首次接受阴茎勃起药物注射的男性在接受 ICI 治疗前和治疗后对疼痛的预期程度与实际经历程度。
我们研究了 51 名在男性健康诊所接受首次 ICI 的患者。通过注射前的评分来判断患者对针相关疼痛的预期程度，通过注射后的评分来判断患者在注射过程中所经历的疼痛程度。所有患者使用标准的 10 分制（0-10）对他们的 ICI 治疗前和治疗后的疼痛进行评分。
对首次接受阴茎内注射的男性，用视觉模拟量表（VAS）来定义 ICI 治疗前和治疗后的疼痛程度（0-10）。
ICI 是治疗 ED 患者的一种安全有效的治疗方法，其疼痛程度明显低于患者预期。
