Ayers David C, Yousef Mohamed, Zheng Hua, Yang Wenyun, Franklin Patricia D
Department of Orthopedics and Physical Rehabilitation, University of Massachusetts Chan Medical School, Worcester, Massachusetts.
Department of Orthopedics and Physical Rehabilitation, University of Massachusetts Chan Medical School, Worcester, Massachusetts; Department of Orthopaedic Surgery, Sohag University, Sohag, Egypt.
J Arthroplasty. 2022 Jun;37(6S):S121-S128. doi: 10.1016/j.arth.2022.02.077. Epub 2022 Feb 26.
Previous studies have evaluated patient dissatisfaction after total knee arthroplasty (TKA) at 1 year, but there is no data about the prevalence of dissatisfaction among TKA patients after prolonged follow-up. The purpose of this study is to determine patient dissatisfaction 5-years after TKA and to identify patient factors predictive of dissatisfaction.
Demographic and clinical data on 4402 patients undergoing primary unilateral TKA between 2012 and 2015 were collected prospectively through the Function and Outcomes Research for Comparative Effectiveness in Total Joint Replacement (FORCE-TJR) comparative effectiveness consortium including diverse community and academic practices distributed across 23 states in the United States. Data collected at 1 year preoperatively and 5 years postoperatively included patient satisfaction (using a 5-point Likert satisfaction scale) and patient-reported outcome measures (PROMs) including the Knee injury and Osteoarthritis Outcome Score (KOOS) and Short-Form health survey (36-item). A univariate analysis of the difference between the satisfied and dissatisfied patients' groups was performed. A multivariate logistic regression model with 95% confidence interval (CI) was used to identify independent predictors of dissatisfaction at 5 years. The regression model was performed after adjusting the following variables: age, gender, body mass index (BMI), Charlson Comorbidity Index (CCI), marital status, smoking, education, and insurance type. The Receiver Operating Characteristic (ROC) analysis was performed with the measurement of area under curve (AUC). Hosmer-Lemeshow goodness of fit test was performed to evaluate the validity of the model.
A total of 12.7% patients (559/4402) reported dissatisfaction 5-years after TKA. Increased BMI, higher CCI, higher Oswestry disability index, and increased number of other painful lower extremities (LE) joints were significantly associated with dissatisfaction. Higher rates of dissatisfaction were present in young patients, patients with less education, and non-White patients. Patient dissatisfaction was significantly associated with poor preoperative and 5-year postoperative PROMs scores and less score improvement from baseline to 5 years (P < .001). The multivariate regression analysis showed that an increased number of other painful LE joints (OR = 1.81; 95% CI (1.14-2.88) (P = .01), increased Oswestry back disability index (OR = 1.40; 95% CI (1.07-1.82) (P = .01), non-White patients (OR = 1.74; 95% CI (1.26-2.40) (P = .001), and minimal preoperative functional disability with KOOS function in daily living (ADL) score ≥70 (OR = 0.64; 95% CI (0.43-0.95) (P = .02) were independent predictive factors for dissatisfaction at 5 years.
A total of 12.7% patients reported dissatisfaction 5-years after TKA. Clinical profiles of the satisfied and dissatisfied patients were captured 5-years after TKA with differences in the preoperative demographic and clinical characteristic variables identified. Risk factors for long-term patient dissatisfaction after TKA have been identified and should be considered during shared decision making while planning for TKA. Surgeons should use these identified risk factors to set realistic expectations for patients at an increased risk for dissatisfaction aiming to optimize their outcomes and increase their long-term satisfaction after TKA.
既往研究评估了全膝关节置换术(TKA)后1年患者的不满意情况,但尚无关于长期随访后TKA患者不满意发生率的数据。本研究的目的是确定TKA术后5年患者的不满意情况,并识别预测不满意的患者因素。
通过全关节置换比较有效性功能与结果研究(FORCE-TJR)比较有效性联盟前瞻性收集了2012年至2015年期间4402例行初次单侧TKA患者的人口统计学和临床数据,该联盟包括美国23个州的不同社区和学术机构。术前1年和术后5年收集的数据包括患者满意度(使用5点李克特满意度量表)和患者报告的结局指标(PROMs),包括膝关节损伤和骨关节炎结局评分(KOOS)和简短健康调查(36项)。对满意和不满意患者组之间的差异进行单因素分析。采用具有95%置信区间(CI)的多因素逻辑回归模型识别5年时不满意的独立预测因素。在调整以下变量后进行回归模型分析:年龄、性别、体重指数(BMI)、查尔森合并症指数(CCI)、婚姻状况、吸烟、教育程度和保险类型。采用曲线下面积(AUC)测量进行受试者操作特征(ROC)分析。进行Hosmer-Lemeshow拟合优度检验以评估模型的有效性。
共有12.7%的患者(559/4402)在TKA术后5年报告不满意。BMI增加、CCI升高、奥斯维斯特里残疾指数升高以及其他疼痛的下肢(LE)关节数量增加与不满意显著相关。年轻患者、教育程度较低的患者和非白人患者的不满意率较高。患者不满意与术前和术后5年的PROMs评分较差以及从基线到术后5年的评分改善较少显著相关(P <.001)。多因素回归分析显示,其他疼痛的LE关节数量增加(OR = 1.81;95%CI(1.14 - 2.88)(P =.01)、奥斯维斯特里背部残疾指数升高(OR = 1.40;95%CI(1.07 - 1.82)(P =.01)、非白人患者(OR = 1.74;95%CI(1.26 - 2.40)(P =.001)以及术前日常生活(ADL)功能残疾最小且KOOS功能评分≥70(OR = 0.64;95%CI(0.43 - 0.