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经肠外瘘内镜置管引流治疗恶性肠梗阻的症状缓解。

Symptomatic resolution of malignant bowel obstruction by endoscopic catheterisation of an enterocutaneous fistula.

机构信息

Leeds Institute of Emergency General Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK

Leeds Institute of Medical Education, University of Leeds, Leeds, UK.

出版信息

BMJ Case Rep. 2022 Feb 28;15(2):e246910. doi: 10.1136/bcr-2021-246910.

DOI:10.1136/bcr-2021-246910
PMID:35228231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8886364/
Abstract

Patients with advanced intra-abdominal malignancy frequently experience nausea and vomiting, however these symptoms can be difficult to manage. A woman in her seventies with high grade primary peritoneal adenocarcinoma developed intermittent small bowel obstruction following extensive surgery. Poor relief was provided by pharmacological approaches and nasogastric tube insertion. Further surgical management was deemed unsuitable due to the significant possibility of complications and likely impairment of the patient's quality of life. A conservative approach was used by using a novel therapeutic intervention: an endoscope was used to visualise an enterocutaneous fistula tract proximal to the obstruction and a gastrostomy catheter was fluoroscopically inserted. This maintained fistula tract patency, permitting drainage of bowel contents and therefore resolving the patient's symptoms. We therefore describe a novel therapeutic approach where endoscopic insertion of a gastrostomy catheter maintained patency of an enterocutaneous fistula, enabling lasting relief of bowel obstruction in a manner acceptable to the patient.

摘要

患有晚期腹腔内恶性肿瘤的患者常出现恶心和呕吐,但这些症状可能难以控制。一位 70 多岁的女性患有高级别原发性腹膜腺癌,在广泛手术后出现间歇性小肠梗阻。药物治疗和鼻胃管插入对缓解症状效果不佳。由于并发症的可能性很大,并且可能会影响患者的生活质量,因此进一步的手术治疗被认为不合适。通过一种新的治疗干预措施采用了保守方法:使用内窥镜观察梗阻近端的肠皮瘘道,并透视插入胃造口管。这保持了瘘道通畅,允许肠内容物引流,从而解决了患者的症状。因此,我们描述了一种新的治疗方法,其中内窥镜插入胃造口管可保持肠皮瘘道通畅,以患者可接受的方式持久缓解肠梗阻。

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本文引用的文献

1
Management of Malignant Bowel Obstruction Associated With GI Cancers.胃肠道癌症相关恶性肠梗阻的管理
J Oncol Pract. 2017 Jul;13(7):426-434. doi: 10.1200/JOP.2017.022210.
2
Recommendations for bowel obstruction with peritoneal carcinomatosis.腹膜癌病所致肠梗阻的治疗建议。
J Pain Symptom Manage. 2014 Jul;48(1):75-91. doi: 10.1016/j.jpainsymman.2013.08.022. Epub 2014 May 4.
3
Palliative management of malignant bowel obstruction in terminally ill patient.晚期患者恶性肠梗阻的姑息治疗
Indian J Palliat Care. 2010 May;16(2):97-100. doi: 10.4103/0973-1075.68403.
4
Palliative venting gastrostomy in malignant intestinal obstruction.恶性肠梗阻的姑息性胃造口排气术
Palliat Med. 2002 Nov;16(6):520-6. doi: 10.1191/0269216302pm590oa.