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使用纤维蛋白胶治疗食管空肠吻合口漏:病例报告

Treatment of Oesophagojejunostomy Leakage With the Use of Fibrin Glue: Case Report.

作者信息

Skałba Władysław, Szymański Piotr, Czarnecki Marek, Zeman Marcin

机构信息

Department of Oncological and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, POL.

出版信息

Cureus. 2022 Jan 24;14(1):e21573. doi: 10.7759/cureus.21573. eCollection 2022 Jan.

DOI:10.7759/cureus.21573
PMID:35228932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8866914/
Abstract

Oesophagojejunostomy leakage after total gastrectomy with D2 lymphadenectomy remains a significant clinical issue. In this paper, we present a case of a 63-year-old female patient who, on the first day after surgery, was diagnosed with oesophagojejunostomy leakage in the chest. The general condition of the patient was stabilized by the implementation of conservative treatment and thoracic drainage. Thanks to covered oesophageal stents, the leakage from the fistula between the anastomotic connection, pleura, and skin was reduced. In the subsequent step, treatment with fibrin glue resulted in complete closure of the fistula. The complementary use of fibrin glue may be effective in the treatment of small oesophagojejunostomy leakages when other endoscopic methods are not sufficient.

摘要

全胃切除联合D2淋巴结清扫术后的食管空肠吻合口漏仍是一个重要的临床问题。在本文中,我们报告了一例63岁女性患者,术后第一天被诊断为胸部食管空肠吻合口漏。通过保守治疗和胸腔引流,患者的一般情况得以稳定。得益于覆膜食管支架,吻合口、胸膜和皮肤之间瘘管的漏液减少。在随后的步骤中,使用纤维蛋白胶治疗使瘘管完全闭合。当其他内镜方法不足时,纤维蛋白胶的辅助使用可能对治疗小的食管空肠吻合口漏有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/8d57b2fcaec5/cureus-0014-00000021573-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/4c3539e18fcd/cureus-0014-00000021573-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/3a9919efaa16/cureus-0014-00000021573-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/0589032361b7/cureus-0014-00000021573-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/8d57b2fcaec5/cureus-0014-00000021573-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/4c3539e18fcd/cureus-0014-00000021573-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/3a9919efaa16/cureus-0014-00000021573-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/0589032361b7/cureus-0014-00000021573-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8866914/8d57b2fcaec5/cureus-0014-00000021573-i04.jpg

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本文引用的文献

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Indian J Gastroenterol. 2021 Jun;40(3):287-294. doi: 10.1007/s12664-021-01152-0. Epub 2021 May 11.
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Gastric cancer.胃癌。
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Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks.内镜下真空辅助闭合装置治疗上消化道漏的结果。
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Modified Endoscopic Vacuum Therapy for Nonhealing Esophageal Anastomotic Leak: Technique Description and Review of Literature.改良内镜下真空疗法治疗食管吻合口不愈合漏:技术描述及文献综述
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Anastomotic Leakage after Upper Gastrointestinal Surgery: Endoscopic Treatment.上消化道手术后吻合口漏:内镜治疗
Visc Med. 2017 Jun;33(3):202-206. doi: 10.1159/000475783. Epub 2017 Jun 14.
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Endoscopic vacuum therapy for various defects of the upper gastrointestinal tract.内镜下真空治疗术治疗上消化道各种缺损。
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Successful endoscopic treatment using biological fibrin glue (Tissucol) for an enterocutaneous fistula occurring after cephalic duodenopancreatectomy.使用生物纤维蛋白胶(Tissucol)成功内镜治疗胰十二指肠切除术后发生的肠皮肤瘘。
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Surg Endosc. 2014 May;28(5):1703-11. doi: 10.1007/s00464-013-3379-4. Epub 2014 Jan 1.