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重大心胸和腹部手术后肺部并发症的风险分层 - 为物理治疗师临床决策制定 PPC 风险预测评分。

Risk Stratification for Postoperative Pulmonary Complications following Major Cardiothoracic and Abdominal Surgery - development of the PPC Risk Prediction Score for Physiotherapists Clinical Decision-making.

机构信息

Department of Physical and Occupational Therapy, Aarhus University Hospital, Aarhus, Denmark.

出版信息

Physiother Theory Pract. 2023 Jun;39(6):1305-1316. doi: 10.1080/09593985.2022.2037795. Epub 2022 Mar 1.

Abstract

INTRODUCTION

Major cardiothoracic or abdominal surgery can lead to the development of postoperative pulmonary complications (PPC), associated with increased morbidity and prolonged length of hospital stay. Preventive chest physiotherapy is routinely provided, but optimization of treatment strategies is needed to improve patient outcome and resource utilization.

OBJECTIVE

To develop a preoperative risk prediction scorelr to assist clinical decision-making regarding physiotherapy interventions.

METHODS

A prospective observational single-center study included 339 of 577 eligible patients admitted for major elective cardiothoracic or abdominal surgery. Primary outcome measure was PPC amendable to chest physiotherapy.

RESULTS

A total of 113 patients (33.3%) developed a PPC. Logistic regression modeling identified four independent predictors of PPC presented with odds ratio (OR) and 95% confidence interval. Reduced lung function (FEV > 50% to <75% OR 2.4 (1.4; 4.3) and FEV ≤ 50% OR 4.7 (1.4;16.0)), Recent unintended weight loss OR 4.5 (1.1; 18.7), Sternotomy OR 3.5 (2.0; 6.0) and Thoraco-abdominal incision OR 4.5 (2.1; 10.1). Based on assigned point values, a score dividing patients into three risk groups was developed. The score had moderate discrimination (-statistic 0.70).

CONCLUSION

By following recommended guidelines (TRIPOD) a preoperative risk prediction score including four predictors of PPC was developed. External validation of the score is currently being investigated.

摘要

简介

重大心胸或腹部手术可导致术后肺部并发症(PPC)的发生,这与发病率增加和住院时间延长有关。常规提供预防性胸部物理疗法,但需要优化治疗策略,以改善患者的预后和资源利用。

目的

开发术前风险预测评分,以协助临床决策关于物理治疗干预。

方法

一项前瞻性观察性单中心研究纳入了 577 名符合条件的择期心胸或腹部大手术患者中的 339 名。主要结局指标是可接受胸部物理治疗的 PPC。

结果

共有 113 名患者(33.3%)发生 PPC。逻辑回归建模确定了 PPC 的四个独立预测因子,表现为比值比(OR)和 95%置信区间。肺功能降低(FEV>50%至<75% OR 2.4(1.4;4.3)和 FEV≤50% OR 4.7(1.4;16.0))、近期非故意体重减轻 OR 4.5(1.1;18.7)、胸骨切开术 OR 3.5(2.0;6.0)和胸腹切开术 OR 4.5(2.1;10.1)。基于分配的点数值,开发了一个将患者分为三个风险组的评分。该评分具有中等的辨别力(-统计量 0.70)。

结论

通过遵循推荐的指南(TRIPOD),开发了一个包括 PPC 四个预测因子的术前风险预测评分。目前正在对该评分进行外部验证。

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