Tekirdağ Namık Kemal Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Tekirdağ, Türkiye
Tekirdağ Namık Kemal Üniversitesi Tıp Fakültesi, Deri ve Zührevi Hastalıkları Anabilim Dalı, Tekirdağ, Türkiye
Turkiye Parazitol Derg. 2022 Mar 1;46(1):54-59. doi: 10.4274/tpd.galenos.2021.93685.
An increase in the counts of the mites that exist in the microbiota of healthy individuals may lead to some dermatological diseases. This study aimed to investigate the prevalence of spp. among patients diagnosed with acne vulgaris, rosacea, perioral dermatitis, seborrheic dermatitis, eczema, and pityriasis folliculorum and the relationship between the demographic and clinical data of such patients and .
This study included 144 patients (70 with acne vulgaris, 6 with pityriasis folliculorum, 15 with seborrheic dermatitis, 39 with rosacea, 8 with eczema, and 6 with perioral dermatitis) and 73 healthy subjects. We evaluated positivity using the standard superficial skin biopsy method in all groups. The presence of more than five mites per square centimeter was considered positive at the diagnosis.
Of the 144 patients included in the study, 107 (74.3%) were female, and 37 (25.7%) were male, while 40 (54.8%) of the 73 healthy subjects were female, and 33 (45.2%) were male. Twenty-one patients (14.5%) and five of the healthy subjects (6.8%) tested positive for . We found that positivity rates in the rosacea and acne vulgaris groups were higher than in the control group. However, this level was not statistically significant (p>0.05). We found the highest positivity rate among the patient groups in the pityriasis folliculorum (4/6, 66.7%), rosacea (8/39, 20.5%), and perioral dermatitis (1/6, 16.7%) groups. Lastly, we found no statistically significant relationship between the demographic and clinical characteristics of the groups and positivity (p>0.05).
The present study is the only study that investigated positivity in six different dermatological diseases. Based on the results, we believe that investigating spp. positivity in dermatological diseases such as acne vulgaris, rosacea, and pityriasis folliculorum would be beneficial for early diagnosis and treatment.
健康个体微生物群中存在的 螨数量增加可能会导致一些皮肤病。本研究旨在调查寻常痤疮、酒渣鼻、口周皮炎、脂溢性皮炎、湿疹和滤泡性糠疹患者中 spp.的患病率，以及这些患者的人口统计学和临床数据与 的关系。
本研究纳入了 144 名患者（70 名寻常痤疮患者、6 名滤泡性糠疹患者、15 名脂溢性皮炎患者、39 名酒渣鼻患者、8 名湿疹患者和 6 名口周皮炎患者）和 73 名健康对照者。我们在所有组中使用标准的浅表皮肤活检方法评估 阳性率。诊断时每平方厘米超过 5 只 螨被认为是阳性。
在纳入研究的 144 名患者中，107 名（74.3%）为女性，37 名（25.7%）为男性，而 73 名健康对照者中，40 名（54.8%）为女性，33 名（45.2%）为男性。21 名（14.5%）患者和 5 名健康对照者（6.8%） 阳性。我们发现酒渣鼻和寻常痤疮组的 阳性率高于对照组，但差异无统计学意义（p＞0.05）。在患者组中，我们发现滤泡性糠疹（4/6，66.7%）、酒渣鼻（8/39，20.5%）和口周皮炎（1/6，16.7%）组的阳性率最高。最后，我们发现各组的人口统计学和临床特征与 阳性率之间无统计学显著关系（p＞0.05）。
本研究是唯一一项在六种不同皮肤病中调查 阳性的研究。基于研究结果，我们认为在寻常痤疮、酒渣鼻和滤泡性糠疹等皮肤病中调查 spp.的阳性率有助于早期诊断和治疗。
