Seibel R M, Wendt B K
Onkologie. 1986 Feb;9(1):43-7. doi: 10.1159/000215959.
In a randomized study 20 patients with non small cell lung cancer were treated for cure at a linear accelerator. Before, during and after treatment levels of immunoglobulins were measured. At the end of radiation therapy levels of IgA, IgG and IgM decreased. After therapy they increased slowly. 3 months after irradiation the average immunoglobulin levels showed a reduction of 16%. After substitution of immunoglobulins no decrease of the levels was seen. After substitution of immunoglobulins the Karnofsky index was significantly higher. Substituted patients showed a lower rate of radiation pneumonitis.
在一项随机研究中，20名非小细胞肺癌患者在直线加速器处接受根治性治疗。在治疗前、治疗期间和治疗后测量免疫球蛋白水平。放射治疗结束时，IgA、IgG和IgM水平下降。治疗后它们缓慢上升。照射3个月后，平均免疫球蛋白水平降低了16%。在替代免疫球蛋白后，未观察到水平下降。替代免疫球蛋白后，卡诺夫斯基指数显著更高。接受替代治疗的患者放射性肺炎发生率较低。
