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抗病毒化疗

Antiviral chemotherapy.

作者信息

Nankervis G A

出版信息

Pediatr Ann. 1986 Jun;15(6):442-4. doi: 10.3928/0090-4481-19860601-06.

Abstract

The above discussion is not intended to be exhaustive but rather to discuss several compounds which are particularly promising at this time. There is no question that great strides have been made in the development of antiviral compounds over the past couple of decades. Many questions remain unanswered such as long-term effects on the host, possible emergence of resistant viruses, optimal routes of administration, and the proper regimens for particular viruses and diseases. In addition, current studies are evaluating combinations of antiviral agents as well as combination therapy involving interferon or antibody or immunity stimulants along with an antiviral agent. Surprising progress has been made to date resulting not only in new therapeutic modalities but promising a new era of progress.

摘要

上述讨论并非详尽无遗,而是旨在探讨目前特别有前景的几种化合物。毫无疑问,在过去几十年里,抗病毒化合物的研发取得了巨大进展。许多问题仍未得到解答,例如对宿主的长期影响、耐药病毒可能的出现、最佳给药途径以及针对特定病毒和疾病的适当治疗方案。此外,目前的研究正在评估抗病毒药物的联合使用,以及涉及干扰素、抗体或免疫刺激剂与抗病毒药物的联合治疗。迄今为止已经取得了惊人的进展,不仅带来了新的治疗方式,而且预示着一个新的进步时代。

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