19271UnitedHealth Group, Eden Prairie, MN, USA.
341495UnitedHealthcare, Minneapolis, MO, USA.
J Aging Health. 2022 Oct;34(6-8):883-892. doi: 10.1177/08982643221074857. Epub 2022 Mar 2.
Using data from a large random sample of U.S. older adults ( = 7982), the effect of loneliness and social isolation on all-cause mortality was examined considering their separate and combined effects.
The UCLA-3 Loneliness Scale and the Social Network Index (SNI) were used to define loneliness and social isolation. Cox proportional hazards regression models were performed.
Among study participants, there were 548 deaths. In separate, adjusted models, loneliness (severe and moderate) and social isolation (limited and moderate social network) were both associated with all-cause mortality. When modeled together, social isolation (limited and moderate social network) along with severe loneliness remained significantly associated with mortality.
Results demonstrate that both loneliness and social isolation contribute to greater risk of mortality within our population of older adults. As the COVID-19 pandemic continues, loneliness and social isolation should be targeted safely in efforts to reduce mortality risk among older adults.
本研究使用来自美国大量老年成年人（n=7982）的随机样本数据，同时考虑到孤独和社会隔离的单独和综合影响，研究孤独和社会隔离对全因死亡率的影响。
本研究使用了 UCLA-3 孤独量表和社会网络指数（SNI）来定义孤独和社会隔离。采用 Cox 比例风险回归模型进行分析。
在研究参与者中，有 548 人死亡。在单独调整的模型中，严重和中度孤独以及有限和中度社会网络的社会隔离均与全因死亡率相关。当同时建模时，有限和中度社会网络的社会隔离以及严重孤独仍然与死亡率显著相关。
结果表明，孤独和社会隔离都会增加我们老年人群体的死亡风险。随着 COVID-19 大流行的持续，应安全地针对孤独和社会隔离采取措施，以降低老年人的死亡风险。
