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坏死梭杆菌胸骨锁骨关节炎的非手术治疗:一例报告。

Nonsurgical management of Fusobacterium necrophorum sternoclavicular septic arthritis: a case report.

机构信息

Harvard Medical School, Boston, MA, 02115, USA.

Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

出版信息

J Med Case Rep. 2022 Mar 3;16(1):90. doi: 10.1186/s13256-022-03316-8.

Abstract

BACKGROUND

To date, the gold-standard treatment for sternoclavicular septic arthritis has been surgery due to the high failure and complication rates of medical treatment. In particular, presentation of Fusobacterium sternoclavicular septic arthritis has been rarely reported and very sparsely investigated, and only one other case report of septic arthritis caused by this pathogen exists in literature.

CASE PRESENTATION

We report a case of an otherwise healthy 38-year-old Caucasian woman who presented with sternoclavicular septic arthritis as a complication of Fusobacterium necrophorum mediastinitis. Our patient underwent successful management through nonstandard, conservative treatment of 7 weeks of intravenous piperacillin + tazobactam followed by 6 weeks of oral amoxicillin + clavulanic acid.

CONCLUSION

We highlight a case of the rare presentation of Fusobacterium necrophorum sternoclavicular septic arthritis that did not require surgical intervention for successful management. Though infection of the sternoclavicular joint is unusual, it continues to be seen in thoracic surgery, and there are increasing numbers of antibiotic-resistant organisms. This case broadens insight into the clinical course and treatment of such conditions. The success of conservative management in this case aligns with the similar nonsurgical course of the one previous report of Fusobacterium sternoclavicular septic arthritis occurrence. Thus, further discussion and thought for reevaluating the current standard practice of surgery for sternoclavicular joint infection is suggested. Our case supports assessing a patient's overall health, causative organism, and extent of infection in interventional course and taking the feasibility of conservative management into more weighted consideration.

摘要

背景

迄今为止,由于医学治疗的高失败率和高并发症率,治疗胸骨锁骨关节炎的金标准一直是手术。特别是,梭菌性胸骨锁骨关节炎的表现很少见且研究甚少,文献中仅报道过一例由该病原体引起的化脓性关节炎。

病例介绍

我们报告了一例 38 岁的健康白人女性,她因坏死梭杆菌纵隔炎并发胸骨锁骨关节炎。我们的患者通过非标准的、为期 7 周的静脉注射哌拉西林+他唑巴坦联合随后 6 周的口服阿莫西林+克拉维酸的保守治疗成功治疗。

结论

我们强调了一例罕见的坏死梭杆菌胸骨锁骨关节炎的表现,无需手术干预即可成功治疗。虽然胸骨锁骨关节感染并不常见,但在胸外科中仍有发生,而且抗生素耐药菌的数量也在增加。该病例拓宽了对这种疾病的临床过程和治疗的认识。在这种情况下,保守治疗的成功与先前报道的一例梭菌性胸骨锁骨关节炎的非手术治疗过程相似。因此,建议进一步讨论和重新评估目前对胸骨锁骨关节感染手术治疗的标准做法。我们的病例支持在干预过程中评估患者的整体健康状况、病原体和感染程度,并更多地考虑保守治疗的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4946/8892743/ec1469e41198/13256_2022_3316_Fig1_HTML.jpg

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