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初次全膝关节置换术后双侧严重异位骨化:巴基斯坦的一例病例报告

Bilateral severe heterotopic ossification following primary total knee arthroplasty: a case report in Pakistan.

作者信息

Iqbal Faizan, Memon Nouman, Noor Syed Shahid, Ahmed Nasir, Sozera Muhammad Farhan, Abro Arsalan

机构信息

Department of Orthopaedic Surgery, Patel Hospital Street 18, Block 4 Gulshan-e-Iqbal, Karachi, Pakistan.

Department of Orthopaedic Surgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.

出版信息

Arthroplasty. 2021 Jan 8;3(1):5. doi: 10.1186/s42836-020-00057-1.

DOI:10.1186/s42836-020-00057-1
PMID:35236464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8796612/
Abstract

The incidence of unilateral minor heterotopic ossification after primary total knee arthroplasty is still unknown, but bilateral severe heterotopic ossification is rare and has not been reported before. Presented in this report is a 60-year-old female patient who developed bilateral knee pain and stiffness 2 weeks after primary total knee arthroplasty. Her weight was 70 kg and body mass index was 32.2. Preoperatively, she had bilateral varus deformity of both knees. X-rays taken 3 months after surgery revealed bilateral severe heterotopic ossification. The patient had been on non-operative treatment (including anti-inflammatory drugs and physiotherapy). There was a marked improvement 6 months after surgery. This case report showed the non-operative treatment may produce acceptable results for patients with severe bilateral heterotopic ossification after primary total knee arthroplasty, and exerted no influence on the final clinical outcome.

摘要

初次全膝关节置换术后单侧轻度异位骨化的发生率尚不清楚,但双侧严重异位骨化较为罕见,此前未见报道。本报告介绍了一名60岁女性患者,她在初次全膝关节置换术后2周出现双侧膝关节疼痛和僵硬。她体重70公斤,体重指数为32.2。术前,她双膝均有内翻畸形。术后3个月的X线片显示双侧严重异位骨化。患者接受了非手术治疗(包括抗炎药物和物理治疗)。术后6个月有明显改善。本病例报告表明,非手术治疗对于初次全膝关节置换术后双侧严重异位骨化的患者可能产生可接受的结果,且对最终临床结局无影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/eeabd05bf237/42836_2020_57_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/25ed3c3dd4fc/42836_2020_57_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/7f71e3815c30/42836_2020_57_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/eeabd05bf237/42836_2020_57_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/25ed3c3dd4fc/42836_2020_57_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/7f71e3815c30/42836_2020_57_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbc/8796612/eeabd05bf237/42836_2020_57_Fig3_HTML.jpg

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本文引用的文献

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Severe heterotopic ossification post total knee arthroplasty in a patient with rheumatoid arthritis: a case report.类风湿关节炎患者全膝关节置换术后严重异位骨化:一例报告
J Surg Case Rep. 2020 Mar 2;2020(3):rjz390. doi: 10.1093/jscr/rjz390. eCollection 2020 Mar.
2
Stiffness post-total knee replacement: A proof of principle study investigating the effect of gene expression analysis of markers of fibrosis.全膝关节置换术后僵硬:一项探究纤维化标志物基因表达分析效果的原理验证研究
Knee. 2019 Aug;26(4):914-922. doi: 10.1016/j.knee.2019.05.005. Epub 2019 Jun 5.
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Severe heterotopic ossification following total knee replacement.
全膝关节置换术后严重异位骨化
Ann R Coll Surg Engl. 2018 Jul;100(6):e150-e153. doi: 10.1308/rcsann.2018.0075. Epub 2018 Apr 25.
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Severe Heterotopic Ossification following Total Knee Replacement.全膝关节置换术后严重异位骨化
Case Rep Orthop. 2014;2014:265489. doi: 10.1155/2014/265489. Epub 2014 Nov 5.
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Limited range of motion caused by heterotopic ossifications in primary total knee arthroplasty: a retrospective study of 27/191 cases.初次全膝关节置换术中异位骨化导致的活动范围受限:一项对27/191例病例的回顾性研究
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Total hip arthroplasty. The role of antiinflammatory medications in the prevention of heterotopic ossification.全髋关节置换术。抗炎药物在预防异位骨化中的作用。
Clin Orthop Relat Res. 1991 Feb(263):78-86.