Department of Child Health, Shiyan Maternal and Child Health Hospital, Shiyan, Hubei, China.
Department of Pediatrics, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, Hubei, China.
Pak J Pharm Sci. 2022 Jan;35(1(Special)):361-364.
To explore the application effect of aminophylline combined with caffeine citrate and GMs in the evaluation of neurodevelopmental treatment and follow-up in high-risk preterm infants. A retrospective analysis of 66 high-risk preterm infants admitted to Hengshui People's Hospital from January 2020 to June 2021 was conducted. The children who received only conventional treatment were set as the control group, while those who received aminophylline and caffeine citrate on the basis of conventional treatment were set as the experimental group, 33 cases each group; GMs were used to evaluate the neurodevelopmental function of the children, and the treatment effect was analyzed. The normal proportion of GMs assessment results in the twisting phase and restless movement phase of the experimental group was superior to the control group (P<0.05); The proportion of children with normal neurodevelopment in the experimental group was significantly higher than that in the control group (P<0.05). Aminophylline in combination with caffeine citrate can help promote the neurodevelopment of children and improve their physical health using GMs assessment in the treatment and follow-up of high-risk preterm infants.
探讨氨茶碱联合枸橼酸咖啡因和 GM 用于高危早产儿神经发育治疗及随访评估中的应用效果。回顾性分析 2020 年 1 月至 2021 年 6 月衡水市人民医院收治的 66 例高危早产儿临床资料，仅接受常规治疗的患儿设为对照组，在此基础上联合氨茶碱与枸橼酸咖啡因治疗的患儿设为实验组，每组 33 例；采用 GM 评估患儿神经发育功能，并分析治疗效果。实验组扭动相、不安运动相 GM 评估结果正常比例优于对照组（P<0.05）；实验组神经发育正常的患儿比例明显高于对照组（P<0.05）。氨茶碱联合枸橼酸咖啡因可帮助高危早产儿神经发育，改善患儿身体健康，GM 评估可用于高危早产儿的治疗及随访中。
