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磁共振成像在骨龄评估中的应用。

The Application of Magnetic Resonance Imaging in Skeletal Age Assessment.

作者信息

Alshamrani Khalaf

机构信息

Radiological Sciences Department, College of Applied Medical Science, Najran University, Najran, Saudi Arabia.

出版信息

Appl Bionics Biomech. 2022 Feb 21;2022:9607237. doi: 10.1155/2022/9607237. eCollection 2022.

Abstract

METHOD

The study includes 80 patients identified from an endocrine clinic, two males and two females from each of 5 age groups (<5, 5 to 7, 8 to 10, 11 to 13, and 14 to 16 years). Skeletal age as determined from an open MRI scanner and radiographs performed on the same day was compared for each child. Two observers assess the skeletal age from radiographs and MRI images independently. After a period of at least three weeks, observers determined the skeletal age of all patients independently. All of the images were in different and random orders, on both of the assessment occasions. The agreement was assessed using the interclass correlation coefficient and Bland Altman plots. . The recurrent use of left-hand radiography in children with chronic conditions might result in the patient being exposed to the same image several times throughout the course of their lives. Use of radiation-free methods such as magnetic resonance imaging (MRI) may be able to assist in reducing the risks associated with radiation exposure, if done properly.

RESULTS

Patients' age ranged from 3 to 16 years, in which the mean of the chronological age was 9.3 years (±2.9) and 9.8 years (±2.7) in girls and boys, respectively. The interrater agreement for skeletal age determination was 0.984 for radiographs and 0.976 for MRI scans. Using the G&P technique, for Observer 1, intraobserver agreement for radiographs and DXA was 0.993 and 0.983, respectively, and 0.995 and 0.994, respectively, for Observer 2. Plotting the rater readings against the line of equality shows no significant differences between readings acquired from radiographs and MRI scans.

CONCLUSION

For the study contribution, it is possible to employ open compact MRI to determine the skeletal age of a person. Our results showed that left-hand MRI scans were of better quality than the radiographs.

摘要

方法

该研究纳入了80名来自内分泌诊所的患者,5个年龄组(<5岁、5至7岁、8至10岁、11至13岁和14至16岁)各有2名男性和2名女性。对每个儿童同一天进行的开放式MRI扫描和X光片所确定的骨龄进行比较。两名观察者分别独立评估X光片和MRI图像的骨龄。经过至少三周的时间后,观察者再次独立确定所有患者的骨龄。在两次评估时,所有图像的顺序均不同且随机排列。使用组内相关系数和布兰德-奥特曼图评估一致性。对于患有慢性病的儿童,反复进行左手X光摄影可能会导致患者在其一生中多次暴露于相同的图像。如果操作得当,使用无辐射方法,如磁共振成像(MRI),可能有助于降低与辐射暴露相关的风险。

结果

患者年龄在3至16岁之间,其中女孩的实际年龄平均为9.3岁(±2.9),男孩为9.8岁(±2.7)。X光片骨龄测定的观察者间一致性为0.984,MRI扫描为0.976。使用G&P技术,对于观察者1,X光片和双能X线吸收法的观察者内一致性分别为0.993和0.983,对于观察者2分别为0.995和0.994。将评分者的读数与平等线作图显示,X光片和MRI扫描获得的读数之间无显著差异。

结论

就本研究而言,使用开放式紧凑型MRI来确定一个人的骨龄是可行的。我们的结果表明,左手MRI扫描的质量优于X光片。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7375/8885254/6387a0ea8186/ABB2022-9607237.001.jpg

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