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吸烟对接受初次髋关节镜检查和盂唇重建患者预后的影响:一项倾向匹配对照研究,随访至少2年

Effect of Cigarette Smoking on Outcomes in Patients Undergoing Primary Hip Arthroscopy and Labral Reconstruction: A Propensity-Matched Controlled Study With Minimum 2-Year Follow-up.

作者信息

Jimenez Andrew E, Lee Michael S, George Tom, Owens Jade S, Maldonado David R, Saks Benjamin R, Lall Ajay C, Domb Benjamin G

机构信息

American Hip Institute Research Foundation, Chicago, Illinois, USA.

American Hip Institute, Chicago, Illinois, USA.

出版信息

Orthop J Sports Med. 2022 Feb 24;10(2):23259671221075642. doi: 10.1177/23259671221075642. eCollection 2022 Feb.

Abstract

BACKGROUND

There is a paucity of literature evaluating the effect of cigarette smoking on outcomes in patients undergoing hip arthroscopy and labral reconstruction.

PURPOSE

(1) To report minimum 2-year patient-reported outcome (PRO) scores for patients who smoke cigarettes and underwent primary hip arthroscopic labral reconstruction and (2) to compare these results with those of a propensity-matched control group of patients who have never smoked.

STUDY DESIGN

Cohort study; Level of evidence, 3.

METHODS

Data were collected for all patients who underwent primary hip arthroscopy for labral reconstruction between January 2011 and January 2019. Patients were eligible for the study if they indicated that they smoked cigarettes within 1 month of surgery and had minimum 2-year postoperative outcome scores for the modified Harris Hip Score (mHHS), Nonarthritic Hip Score (NAHS), and the visual analog scale (VAS) for pain. The percentage of patients achieving the minimal clinically important difference (MCID) and patient-acceptable symptom state (PASS) was recorded. Rates of revision surgery were also documented. These patients were then propensity matched in a 1:3 ratio to patients who had never smoked (controls) for comparison.

RESULTS

A total of 20 patients (20 hips) were included with a mean follow-up of 39.9 ± 13.0 months and mean age of 41.4 ± 10.4 years. These patients demonstrated significant improvement from preoperatively to the minimum 2-year follow-up for mHHS, NAHS, and VAS ( < .05). They also achieved MCID for mHHS and VAS at acceptable rates, 70% for both. When outcomes were compared with those of 60 control patients (60 hips), patients who smoke demonstrated lower preoperative PRO scores but similar minimum 2-year postoperative PRO scores for mHHS and NAHS. Patients who smoke demonstrated lower rates of achieving PASS for mHHS (55% vs 75%) and NAHS (40% vs 61.7%) compared with controls; however, these findings were not statistically significant. Rates of secondary surgery were statistically significantly higher in the smoking group compared with controls (25% vs 5%; = .031). Survivorship for the smoking patients was 80% and 98.3% for the control group. At the two-year mark survivorship was 90% for the smoking group and 100% for the control group ( = .06).

CONCLUSION

While smokers can still derive significant improvement from hip arthroscopy, their ultimate functional outcome and rate of secondary surgeries are inferior to those of nonsmokers. As smoking is a significant and modifiable risk factor, we should continue to counsel smokers on smoking cessation prior to and after surgery.

摘要

背景

关于吸烟对接受髋关节镜检查和盂唇重建患者预后影响的文献较少。

目的

(1)报告吸烟且接受初次髋关节镜下盂唇重建患者至少2年的患者报告结局(PRO)评分,(2)将这些结果与倾向评分匹配的从未吸烟对照组患者的结果进行比较。

研究设计

队列研究;证据等级,3级。

方法

收集2011年1月至2019年1月期间接受初次髋关节镜下盂唇重建的所有患者的数据。如果患者表示在手术前1个月内吸烟,并且有改良Harris髋关节评分(mHHS)、非关节炎髋关节评分(NAHS)和疼痛视觉模拟量表(VAS)的至少2年术后结局评分,则符合纳入本研究的条件。记录达到最小临床重要差异(MCID)和患者可接受症状状态(PASS)的患者百分比。还记录了翻修手术率。然后将这些患者与从未吸烟的患者(对照组)按1:3的比例进行倾向评分匹配以进行比较。

结果

共纳入20例患者(20髋),平均随访39.9±13.0个月,平均年龄41.4±10.4岁。这些患者从术前到至少2年随访时,mHHS、NAHS和VAS均有显著改善(P<0.05)。他们在mHHS和VAS方面也以可接受的比率达到了MCID,两者均为70%。当将结果与60例对照患者(60髋)的结果进行比较时,吸烟患者术前PRO评分较低,但mHHS和NAHS的至少2年术后PRO评分相似。与对照组相比,吸烟患者在mHHS(55%对75%)和NAHS(40%对61.7%)方面达到PASS的比率较低;然而,这些发现无统计学意义。吸烟组二次手术率与对照组相比有统计学显著差异(25%对5%;P=0.031)。吸烟患者的生存率为80%,对照组为98.3%。在两年时,吸烟组生存率为90%,对照组为100%(P=0.06)。

结论

虽然吸烟者仍能从髋关节镜检查中获得显著改善,但其最终功能结局和二次手术率低于不吸烟者。由于吸烟是一个重要且可改变的风险因素,我们应继续在手术前后建议吸烟者戒烟。

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