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初始诊断为行为变异型额颞叶痴呆个体神经精神症状的持续长期改善:一例报告

Sustained Long-term Improvement in Neuropsychiatric Symptoms of an Individual With Initial bvFTD Diagnosis: A Case Report.

作者信息

Kim Esther S, Pliskin Neil H, Caserta Maria T

机构信息

Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois.

出版信息

Cogn Behav Neurol. 2022 Mar 3;35(1):76-82. doi: 10.1097/WNN.0000000000000298.

DOI:10.1097/WNN.0000000000000298
PMID:35239601
Abstract

The behavioral variant of frontotemporal dementia (bvFTD) is a neurodegenerative disease that is diagnosed by progressive neuropsychiatric changes and supportive neuroimaging. Making an accurate diagnosis of bvFTD is a challenging process that can be complicated by the presence of a subset of nonprogressive, or phenocopy, cases whose symptoms remain stable. Our patient, who presented with neuropsychiatric symptoms that are characteristic of bvFTD, improved and stabilized after thorough neuropsychiatric and neuropsychological evaluation and treatment. Our case illustrates that, despite diagnostic uncertainties, appropriate evaluation and treatment can lead to improvement and stabilization of neuropsychiatric symptoms in individuals presumed to have bvFTD.

摘要

额颞叶痴呆的行为变异型(bvFTD)是一种神经退行性疾病,通过进行性神经精神变化及辅助神经影像学检查来诊断。准确诊断bvFTD是一个具有挑战性的过程,可能会因存在一部分症状保持稳定的非进行性或表型相似病例而变得复杂。我们的患者表现出bvFTD的典型神经精神症状,在经过全面的神经精神和神经心理学评估及治疗后病情得到改善并稳定下来。我们的病例表明,尽管存在诊断不确定性,但适当的评估和治疗可使疑似患有bvFTD的个体的神经精神症状得到改善和稳定。

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