巴西艾滋病毒和艾滋病专门服务机构中感染 HIV 的无症状神经梅毒患者：一项横断面研究。
Asymptomatic Neurosyphilis in HIV infected patients at a Brazilian HIV and AIDS specialized service: a cross sectional study.
机构信息
Universidade Estadual de Maringá, Programa de Pós-Graduação em Ciências da Saúde, Maringá , PR, Brasil.
Universidade Estadual de Maringá, Departamento de Estatística, Maringá, PR, Brasil.
出版信息
Rev Soc Bras Med Trop. 2022 Feb 25;55:e0418. doi: 10.1590/0037-8682-0418-2021. eCollection 2022.
BACKGROUND
Many human immunodeficiency virus (HIV) and syphilis co-infected patients are not diagnosed, which may evolve into asymptomatic neurosyphilis (ANS). We studied the occurrence of ANS an HIV-infected population.
METHODS
This was a cross-sectional study of cerebrospinal fluid (CSF) samples collected from patients co-infected with HIV and Treponema pallidum. Social-demographic and clinical-laboratory characteristics were studied.
RESULTS
Of the 348 patients infected with HIV, 33 (9.5%) had reagent treponemic and non-treponemic tests. CSF was collected from 19 asymptomatic patients. Of these, 8 (42.1%) presented with laboratory alterations suggestive of ANS.
CONCLUSION
Social-demographic and clinical-laboratory variables should be considered for the indication of CSF collection.
背景
许多人类免疫缺陷病毒（HIV）和梅毒合并感染患者未被诊断，这可能会发展为无症状神经梅毒（ANS）。我们研究了 HIV 感染人群中 ANS 的发生情况。
方法
这是一项对 HIV 和梅毒螺旋体合并感染患者的脑脊液（CSF）样本进行的横断面研究。研究了社会人口统计学和临床实验室特征。
结果
在 348 名感染 HIV 的患者中，有 33 名（9.5%）的试剂梅毒螺旋体和非梅毒螺旋体检测呈阳性。从 19 名无症状患者中采集了 CSF。其中，8 名（42.1%）患者出现了实验室改变，提示 ANS。
结论
应考虑社会人口统计学和临床实验室变量来指示 CSF 采集。
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