Universidade de Pernambuco, Postgraduate Program in Health Sciences - Recife (PE), Brazil.
Universidade de Pernambuco, Postgraduate Program in Therapeutic Innovation - Recife (PE), Brazil.
Rev Assoc Med Bras (1992). 2022 Jan;68(1):19-23. doi: 10.1590/1806-9282.20210199.
The objective of this study was to analyze the association between orthostatic changes in blood pressure and mortality in elderly cardiopath patients.
A cohort of 455 elderly cardiopath patients, monitored at a referral outpatient cardiology clinic in Pernambuco, Brazil, from October 2015 to July 2018. The exposure groups were formed according to their orthostatic changes in blood pressure following the requirements of the Brazilian Guidelines for Hypertension.
Orthostatic hypotension was present in 46 patients (10.1%), 91 had orthostatic hypertension (20%), and 318 had no orthostatic alterations (69.9%). There were 52 deaths during follow-up. The results demonstrated that there was no statistically significant association between orthostatic hypotension and overall mortality (HR 1.30; 95%CI 0.53-3.14; p=0.567) nor between orthostatic hypertension and overall mortality (HR 0.95; 95%CI 0.65-1.39; p=0.34). Survival in relation to the exposure groups presented no statistically significant difference (p=0.504).
There was a low frequency of orthostatic hypotension and a mild high frequency of orthostatic hypertension when compared with previous studies, and no association was observed with overall mortality or with the survival time of elderly patients with heart disease.
本研究旨在分析老年心脏病患者血压体位变化与死亡率之间的关系。
该队列纳入了 2015 年 10 月至 2018 年 7 月在巴西伯南布哥州一家转诊门诊心内科诊所接受监测的 455 例老年心脏病患者。根据巴西高血压指南的要求，将暴露组分为血压体位变化组。
46 例（10.1%）患者存在体位性低血压，91 例（20%）患者存在体位性高血压，318 例（69.9%）患者无体位性改变。随访期间共发生 52 例死亡。结果表明，体位性低血压与总死亡率之间无统计学显著关联（HR 1.30；95%CI 0.53-3.14；p=0.567），体位性高血压与总死亡率之间也无统计学显著关联（HR 0.95；95%CI 0.65-1.39；p=0.34）。暴露组之间的生存情况无统计学显著差异（p=0.504）。
与既往研究相比，本研究中体位性低血压的发生率较低，体位性高血压的轻度高发生率，且与总死亡率或老年心脏病患者的生存时间均无关联。
