Lee Dong Hoon, Lim Sang Chul
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Hwasun Hospital, Hwasun, South Korea.
J Craniofac Surg. 2022 Oct 1;33(7):e699-e701. doi: 10.1097/SCS.0000000000008601. Epub 2022 Feb 24.
Fibrous dysplasia (FD) is a benign, idiopathic skeletal disorder, in which the normal bone and marrow are replaced by fibrous tissue and immature woven bone. The authors aim to analyze the long-term results of patients diagnosed with FD of the paranasal sinuses via imaging or surgical biopsy.
The authors retrospectively enrolled 21 patients with FD of the paranasal sinuses from 2006 to 2021.
The mean age at the time of diagnosis of FD of the paranasal sinuses was very high at 45.9 years. The most common site ofoccurrence was the sphenoid sinus (71.4%). During the mean follow-up period of 52.8 months, there was no significant change in the size of FD of the paranasal sinuses, and there was no worsening of symptoms or complications. Endoscopic sinus surgery was performed in 16 patients (76.2%), of which 13 underwent only biopsy and 3 underwent partial resection.
The most common site of FD of the paranasal sinuses was the sphenoid sinus, and the age at diagnosis was higher thanthat of patients with FD at other sites. Observation with serial radiologic examinations is recommended for asymptomatic FD of the para-nasal sinuses.
骨纤维异常增殖症（FD）是一种良性特发性骨骼疾病，其中正常骨和骨髓被纤维组织和未成熟的编织骨所取代。作者旨在分析通过影像学或手术活检诊断为鼻窦骨纤维异常增殖症患者的长期结果。
作者回顾性纳入了2006年至2021年期间21例鼻窦骨纤维异常增殖症患者。
鼻窦骨纤维异常增殖症诊断时的平均年龄很高，为45.9岁。最常见的发病部位是蝶窦（71.4%）。在平均52.8个月的随访期内，鼻窦骨纤维异常增殖症的大小无显著变化，症状或并发症也未加重。16例患者（76.2%）接受了鼻内镜鼻窦手术，其中13例仅进行了活检，3例进行了部分切除。
鼻窦骨纤维异常增殖症最常见的部位是蝶窦，诊断年龄高于其他部位骨纤维异常增殖症患者。对于无症状的鼻窦骨纤维异常增殖症，建议进行系列影像学检查观察。
