Department of Human Nutrition, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland;
Department of General Surgery and Clinical Nutrition, Centre of Postgraduate Medical Education, Warsaw, Poland.
In Vivo. 2022 Mar-Apr;36(2):884-889. doi: 10.21873/invivo.12777.
BACKGROUND/AIM: End jejunostomy syndrome is a type of short bowel syndrome (SBS) in which the jejunum forms the end of the bowel, as a result of resection or exclusion of the ileum and colon. It is associated with a high risk of dehydration, electrolyte imbalance, and malnutrition due to excessive stomal losses.
In this retrospective study, we analyzed the medical records of sixteen adult patients with SBS and high-output end jejunostomy syndrome who received thickened fluids during their hospitalization in the home parenteral nutrition unit. The main parameter considered was daily stoma excretion volume, measured by 24-h collection. Values were compared between days when patients drank the daily amount of 600 ml of water, and days when patients ingested the same amount of water but mixed with thickening powder to achieve a mildly thick consistency.
Median volumes of end jejunostomy output were significantly lower when patients consumed the mixture of water and thickening powder, compared with drinking water without additives (550.0 ml/d vs. 811.9 ml/d, p=0.002).
These preliminary results demonstrate a potential benefit of thickening powder for the nutritional management of patients with SBS type I, and point to the need for further randomized clinical studies with larger patient groups.
背景/目的：回肠造口综合征是一种短肠综合征（SBS），由于回肠和结肠的切除或排除，空肠形成了肠的末端。由于过度的造口损失，它与脱水、电解质失衡和营养不良的高风险相关。
在这项回顾性研究中，我们分析了在家庭肠外营养单位住院期间接受增稠液的 16 名成人 SBS 伴高输出回肠造口综合征患者的病历。主要考虑的参数是通过 24 小时收集测量的每日造口排出量。将患者饮用每日 600 毫升水的天数与患者饮用相同量的水但混合增稠剂以达到轻度浓稠的天数进行比较。
与饮用无添加剂的水相比，当患者饮用水和增稠剂的混合物时，回肠造口输出量的中位数明显更低（550.0 毫升/天与 811.9 毫升/天，p=0.002）。
这些初步结果表明增稠剂对 I 型 SBS 患者的营养管理可能有益，并指出需要进一步进行具有更大患者群体的随机临床试验。
