Khalaf Rawan M, Almudhi Abdullazez A
Postgraduate Student for the degree of Doctor of Science in Dentistry (DScD), Department of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Assistant Professor, Division of Orthodontics, Department of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Saudi Dent J. 2022 Feb;34(2):129-135. doi: 10.1016/j.sdentj.2021.12.008. Epub 2021 Dec 23.
Bone remodeling and orthodontic tooth movement (OTM) are controlled by certain essential molecules, one of which is vitamin D. Increased levels of vitamin D have been associated with increased rates of OTM. The purpose of this study was to determine the effect of vitamin D deficiency on the rate of OTM, and to determine their association after applying orthodontic forces.
Wistar rats were divided into two groups: control group with average vitamin D levels and experimental group with induced vitamin D deficiency. Orthodontic appliances were fixed to initiate tooth movement. Distance between the reference teeth were measured in millimeters on day zero, and repeated every 7 days, till day 21.
A significant difference within the experimental group was found; as well as within the control group, there was also no significant interaction between time and the type of group.
The rate of Orthodontic tooth movement was not affected by induced vitamin D deficiency in rats.
骨重塑和正畸牙齿移动（OTM）受某些关键分子调控，其中之一是维生素D。维生素D水平升高与OTM速率增加有关。本研究旨在确定维生素D缺乏对OTM速率的影响，并在施加正畸力后确定它们之间的关联。
将Wistar大鼠分为两组：维生素D水平正常的对照组和诱导维生素D缺乏的实验组。固定正畸矫治器以启动牙齿移动。在第0天以毫米为单位测量参考牙齿之间的距离，并每7天重复测量一次，直至第21天。
在实验组内发现有显著差异；在对照组内也有显著差异，并且时间与组类型之间没有显著相互作用。
诱导的维生素D缺乏对大鼠正畸牙齿移动速率没有影响。
