Yacoub O F, Morrow D H
Am J Psychiatry. 1986 Aug;143(8):1027-9. doi: 10.1176/ajp.143.8.1027.
The malignant hyperthermia syndrome is a rare hypermetabolic state that occurs in patients after the administration of certain drugs, most frequently anesthetics and/or succinylcholine. In view of the widespread use of succinylcholine to induce muscle relaxation prior to ECT, it is important that the individual who administers succinylcholine in this setting be familiar with the syndrome and its treatment. This report reviews what is known about malignant hyperthermia and proposes a course of action when the syndrome occurs in a patient undergoing ECT or a patient with known susceptibility to malignant hyperthermia needs ECT.
恶性高热综合征是一种罕见的高代谢状态,发生于患者使用某些药物之后,最常见的是麻醉剂和/或琥珀酰胆碱。鉴于在ECT前广泛使用琥珀酰胆碱诱导肌肉松弛,在此情况下使用琥珀酰胆碱的人员熟悉该综合征及其治疗方法很重要。本报告回顾了关于恶性高热的已知情况,并提出了在接受ECT的患者中发生该综合征或已知对恶性高热易感的患者需要ECT时的应对措施。