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COVID-19 阳性患者接受心脏手术:可能是缺氧-溶血-炎症反应三联征的一种表现。

COVID-19 Positive Cohort Undergoing Cardiac Surgery: A Possible Un(3H)oly Trinity of Hypoxia-Hemolysis-Hyperinflammation.

机构信息

Department of Cardiac Anaesthesia, Atal Bihari Vajpayee Institute of Medical Sciences (ABVIMS) and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, India.

Department of Anaesthesia, Atal Bihari Vajpayee Institute of Medical Sciences (ABVIMS) and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, India.

出版信息

Braz J Cardiovasc Surg. 2022 Aug 16;37(4):587-590. doi: 10.21470/1678-9741-2021-0077.

DOI:10.21470/1678-9741-2021-0077
PMID:35244375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9423808/
Abstract

While the fraternity continues to ponder on the mechanisms by which coronavirus disease (COVID-19) positivity affects the outcome of cardiac surgical subset, we put forth a 3H (Hypoxia-Hemolysis-Hyperinflammation) trilogy aimed at elucidating the liaison between cardiopulmonary bypass (commonly employed for cardiac surgical conduct) and COVID-19 infection. A sound comprehension of the same can doubtlessly assist the perioperative team in staging a well-directed pathophysiology-driven management approach.

摘要

虽然兄弟会仍在思考冠状病毒病 (COVID-19) 阳性如何影响心脏外科亚组的结果的机制,但我们提出了一个 3H(缺氧-溶血-高度炎症)三部曲,旨在阐明体外循环(常用于心脏外科手术)与 COVID-19 感染之间的联系。对其的充分理解无疑可以帮助围手术期团队制定出一种针对病理生理学的有针对性的管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7349/9423808/e115ea21514e/rbccv-37-04-0587-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7349/9423808/e115ea21514e/rbccv-37-04-0587-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7349/9423808/e115ea21514e/rbccv-37-04-0587-g01.jpg

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本文引用的文献

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Neurologia (Engl Ed). 2021 Sep;36(7):562-563. doi: 10.1016/j.nrleng.2021.03.004.
2
Methylene blue: Subduing the post COVID-19 blues!亚甲蓝:战胜新冠后情绪低落!
Med Hypotheses. 2021 May;150:110574. doi: 10.1016/j.mehy.2021.110574. Epub 2021 Mar 23.
3
Postoperative inflammation to "hyper"-inflammation: cryptic COVID-19 connections!术后炎症到“过度”炎症:隐匿的新冠病毒关联!
Paediatr Anaesth. 2021 Mar;31(3):380-381. doi: 10.1111/pan.14121.
4
Left-ventricular diastolic dysfunction in coronavirus disease: opening Pandora's box!冠状病毒病中的左心室舒张功能障碍:打开潘多拉魔盒!
Korean J Anesthesiol. 2021 Dec;74(6):557-558. doi: 10.4097/kja.21010. Epub 2021 Jan 13.
5
Haematological inflammatory prognostication in COVID-19: Points to ponder!COVID-19中的血液学炎症预后:需思考的要点!
Am J Emerg Med. 2021 Jul;45:565-566. doi: 10.1016/j.ajem.2020.12.070. Epub 2020 Dec 29.
6
Inhaled milrinone for sick COVID-19 cohort: A pathophysiology driven hypothesis!吸入米力农治疗新冠重症患者队列:基于病理生理学的假说!
Med Hypotheses. 2021 Jan;146:110441. doi: 10.1016/j.mehy.2020.110441. Epub 2020 Nov 29.
7
Predicting Lactate Elevation in Neonatal Cardiac Surgery: Can the Sugars be Overlooked?
J Cardiothorac Vasc Anesth. 2021 Jul;35(7):2243-2244. doi: 10.1053/j.jvca.2020.11.028. Epub 2020 Nov 20.
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J Cardiothorac Vasc Anesth. 2020 Dec;34(12):3193-3196. doi: 10.1053/j.jvca.2020.09.132. Epub 2020 Oct 2.
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J Cardiothorac Vasc Anesth. 2021 Nov;35(11):3315-3318. doi: 10.1053/j.jvca.2020.10.021. Epub 2020 Oct 17.
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J Card Surg. 2020 Dec;35(12):3650-3652. doi: 10.1111/jocs.14982. Epub 2020 Nov 1.