Martin M S
Bull Cancer. 1978;65(1):49-52.
Experimental models of colonic carcinoma chemically induced in rats explored the effects of several factors involved in colon carcinogenesis: high fat level of the diet, quality and quantity of fat, fecal excretion of neutral and acid steroids, intestinal microflora and fiber content of the diet. They suggested an association linking colon cancer to dietary fat and fecal acids and neutral sterols.
对大鼠化学诱导的结肠癌实验模型进行了研究,探讨了结肠癌发生过程中涉及的几个因素的影响:饮食中的高脂肪水平、脂肪的质量和数量、中性和酸性类固醇的粪便排泄、肠道微生物群以及饮食中的纤维含量。这些研究表明结肠癌与饮食脂肪、粪便酸和中性固醇之间存在关联。