Tunis Med. 2021;99(6):623-631.
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease with a multi-systemic impact that can be complicated by psycho-affective disorders.
To determinethe frequency of anxiety and depression in patients followed for stable COPD in a university hospital-center in Tunisand to determine the predictors of their onset.
This was an analytical cross-sectional studyof patients followed for stable COPD at the pulmonology department of the Mongi Slim La Marsa Hospital. The symptoms of COPD were assessed by the Chronic obstructive pulmonary disease Assessment Test (CAT), its severity by the GOLD 2020 classification and the screening of psycho-affective disorders by the HAD scale.
One hundred and three patients were enrolled, with an average age of 64 years. The prevalence of anxiety was 44.7% and that of depression was 33.9%with 26.2% of patients with a major depressive episode. In multivariate analysis by binary logistic regression, the highest values of CAT score were associated with anxiety, depression, and the onset of a major depressive episode. Other factors associated with anxiety and the onset of a major depressive episode were associated heart rhythm disorders and the lowest BMI values. In addition, the female gender was associated with the onset of a major depressive episode.
Anxiety and depression are common in Tunisian patients with COPD, hence the interest of their systematic screening.
慢性阻塞性肺疾病(COPD)是一种具有多系统影响的慢性肺部疾病,可并发心理-情感障碍。
在突尼斯的一所大学医院中心,确定稳定期 COPD 患者的焦虑和抑郁频率,并确定其发病的预测因素。
这是一项在 Mongi Slim La Marsa 医院肺病科接受稳定期 COPD 治疗的患者的分析性横断面研究。通过慢性阻塞性肺病评估测试(CAT)评估 COPD 症状,通过 GOLD 2020 分类评估其严重程度,通过 HAD 量表筛查心理-情感障碍。
共纳入 103 例患者,平均年龄为 64 岁。焦虑的患病率为 44.7%,抑郁的患病率为 33.9%,其中 26.2%的患者患有重度抑郁发作。通过二元逻辑回归的多变量分析,CAT 评分最高与焦虑、抑郁和重度抑郁发作的发生有关。与焦虑和重度抑郁发作相关的其他因素与心律失常和最低 BMI 值有关。此外,女性与重度抑郁发作的发生有关。
焦虑和抑郁在突尼斯 COPD 患者中很常见,因此系统筛查很有意义。