Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan.
Department of Cardiovascular Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong City, 637000, Sichuan Province, China.
BMC Pulm Med. 2024 Aug 12;24(1):390. doi: 10.1186/s12890-024-03202-7.
Anxiety and depression are prevalent comorbidities in patients with chronic obstructive pulmonary disease (COPD). However, existing research has yielded conflicting findings regarding the effects of social frailty on anxiety and depression. The primary aim of this study is to validate the relationship between social frailty and social support with anxiety and depression in patients with acute exacerbations of COPD (AECOPD) and to investigate whether social support could explain the variations in prior study outcomes for patients with AECOPD.
Of the 315 patients hospitalized with AECOPD at the respiratory intensive care unit of a large tertiary care institution in Sichuan Province of China, between August 2022 and June 2023 who were surveyed, 306 were included in the analysis after excluding missing data. We conducted a logistic regression analysis to examine the associations of social frailty and social support with anxiety and depression and performed mediation analyses to examine whether social support mediates the relationship of social frailty with anxiety and depression.
The logistic regression analysis revealed that social frailty did not associate anxiety or depression in patients with AECOPD. The mediation analysis supported this idea and indicated that while social frailty does not directly influence anxiety or depression, it can through social support.
The findings suggest that while social frailty may not directly impact anxiety or depression in patients with AECOPD, social support plays a crucial mediating role. Enhancing social support can indirectly alleviate anxiety and depression among these patients. Enhancing social support networks should thus be prioritized by healthcare providers and family members to improve mental health outcomes in this patient population.
焦虑和抑郁是慢性阻塞性肺疾病（COPD）患者常见的合并症。然而，现有研究对于社会脆弱性对焦虑和抑郁的影响得出了相互矛盾的结论。本研究的主要目的是验证社会脆弱性和社会支持与 COPD 急性加重（AECOPD）患者焦虑和抑郁之间的关系，并探讨社会支持是否可以解释 AECOPD 患者先前研究结果的变化。
在四川省一家大型三级医疗机构的呼吸重症监护病房住院的 315 名 AECOPD 患者中，对 2022 年 8 月至 2023 年 6 月期间接受调查的患者进行了分析，在排除缺失数据后，有 306 名患者被纳入分析。我们进行了逻辑回归分析，以检验社会脆弱性和社会支持与焦虑和抑郁的关系，并进行了中介分析，以检验社会支持是否调节社会脆弱性与焦虑和抑郁的关系。
逻辑回归分析表明，社会脆弱性与 AECOPD 患者的焦虑或抑郁无关。中介分析支持了这一观点，并表明虽然社会脆弱性不会直接影响焦虑或抑郁，但它可以通过社会支持。
这些发现表明，虽然社会脆弱性可能不会直接影响 AECOPD 患者的焦虑或抑郁，但社会支持起着至关重要的中介作用。增强社会支持可以间接地减轻这些患者的焦虑和抑郁。因此，医疗保健提供者和家庭成员应优先增强社会支持网络，以改善这一患者群体的心理健康结果。
