Thomas I L, Chenoweth J N, Tronc G N, Johnson I R
Aust N Z J Obstet Gynaecol. 1986 Feb;26(1):30-5. doi: 10.1111/j.1479-828x.1986.tb01524.x.
Ripening of the unfavourable cervix prior to induction of labour using traction on a Foley catheter (32 patients) was compared with 40 mg of prostaglandin F2 alpha in Tylose gel applied to the external cervical os and held in place for 12 hours with a vaginal diaphragm (25 patients). Each patient in the above groups had a modified Bishop score of 0-3 and was randomly allocated to one or other group. Comparison was made with a further 25 patients in whom the cervical score was 4-6. Timing of amniotomy and commencement of Syntocinon infusion were equivalent for all patients. Prostaglandins conferred no advantage over Foley catheter in terms of amniotomy-delivery interval, operative delivery rate, and condition of the baby one minute after birth. The disadvantages of prostaglandins for cervical ripening are a longer preparation-delivery interval, and cost ($77 versus $4.75 for the Foley catheter). Currently, prostaglandins are not officially approved for use in Australia for induction of labour. It is suggested, therefore, that the Foley catheter is preferable for ripening the unfavourable cervix as a prelude to amniotomy.
在引产时，对32例患者使用Foley导管牵引使未成熟宫颈成熟，将其与25例患者进行比较，这25例患者在宫颈外口涂抹含40mg前列腺素F2α的泰洛糖凝胶并用阴道隔膜固定12小时。上述两组中的每位患者改良Bishop评分均为0 - 3分，并随机分配至其中一组。另外选取25例宫颈评分为4 - 6分的患者进行比较。所有患者的破膜时间和缩宫素输注开始时间相同。在破膜至分娩间隔、手术分娩率以及出生后一分钟时婴儿状况方面，前列腺素相比Foley导管并无优势。前列腺素用于宫颈成熟的缺点是准备至分娩间隔更长且成本更高（前列腺素为77美元，Foley导管为4.75美元）。目前，前列腺素在澳大利亚未获官方批准用于引产。因此，建议在破膜前使用Foley导管使未成熟宫颈成熟更为可取。
