Almér L O, Kjellström T
Atherosclerosis. 1986 Jul;61(1):81-5. doi: 10.1016/0021-9150(86)90116-4.
Bezafibrate was given to 23 hypertriglyceridemic but otherwise healthy middle-aged men in a double-blind, cross-over study to evaluate its effect on the components of the fibrinolytic system as well as on ATIII, FVIIIR: Ag, FVIII: C and platelet aggregation. Fibrinogen dropped markedly (P less than 0.05) and there was a small but significant fall of ATIII. The second wave of platelet aggregation was found much less frequently than in controls (P less than 0.001). Bezafibrate seemed to decrease the rate of formation of the first wave platelet aggregation.
在一项双盲、交叉研究中，对23名患有高甘油三酯血症但其他方面健康的中年男性给予苯扎贝特，以评估其对纤溶系统成分以及抗凝血酶III（ATIII）、因子VIII相关抗原（FVIIIR:Ag）、因子VIII促凝成分（FVIII:C）和血小板聚集的影响。纤维蛋白原显著下降（P<0.05），抗凝血酶III有小幅但显著的下降。与对照组相比，第二波血小板聚集的出现频率要低得多（P<0.001）。苯扎贝特似乎降低了第一波血小板聚集的形成速率。
