Department of Gastroenterology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Eur J Med Res. 2022 Mar 5;27(1):36. doi: 10.1186/s40001-022-00665-4.
Ischemic colitis is the most prevalent ischemic injury of the gastrointestinal tract. The majority of patients with mild ischemic colitis usually achieve complete clinical recovery shortly. However, the predictors of longer hospital stay duration are unclear. This study aimed to evaluate the predictors of hospital stay duration for patients with mild ischemic colitis.
We retrospectively evaluated 100 patients with mild ischemic colitis between January 2010 and December 2020 at Xiangya Hospital (a tertiary care center). The clinical characteristics and therapeutic drugs of patients who were hospitalized for ≤ 8 days and ≥ 12 days were compared.
Of the 100 patients included, 63 (63%) were hospitalized for ≤ 8 days and 37 (37%) were hospitalized for ≥ 12 days. Patients with cerebrovascular disease (29.7% vs. 11.1%, p = 0.019) and abdominal surgical history (29.7% vs. 7.9%, p = 0.004) were more likely to be hospitalized for ≥ 12 days than for ≤ 8 days. The D-dimer levels [0.78 (0.41-1.82) vs. 0.28 (0.16-0.73), p = 0.001] and positive fecal occult blood test results (86.5% vs. 60.3%, p = 0.006) were higher in patients who were hospitalized for ≥ 12 days than in those who were hospitalized for ≤ 8 days. Probiotic use was greater in patients hospitalized for ≤ 8 days (76.2% vs. 54.1%, p = 0.022). Multivariate analysis indicated that cerebrovascular disease (odds ratio [OR] = 4.585; 95% confidence interval [CI] 1.129-18.624; p = 0.033), abdominal surgical history (OR = 4.551; 95% CI 1.060-19.546; p = 0.042), higher D-dimer levels (OR = 1.928; 95% CI 1.024-3.632; p = 0.042), and higher positive fecal occult blood test results (OR = 7.211; 95% CI 1.929-26.953; p = 0.003) were associated with longer hospital stays.
Cerebrovascular disease, abdominal surgical history, higher D-dimer levels, and higher positive fecal occult blood test results are independent and significant factors that influence longer hospital stays for patients with mild ischemic colitis. Probiotics helped reduce hospital stay in these patients.
缺血性结肠炎是胃肠道最常见的缺血性损伤。大多数轻度缺血性结肠炎患者通常在短时间内完全临床康复。然而，住院时间延长的预测因素尚不清楚。本研究旨在评估轻度缺血性结肠炎患者住院时间的预测因素。
我们回顾性评估了 2010 年 1 月至 2020 年 12 月在湘雅医院（三级医疗中心）收治的 100 例轻度缺血性结肠炎患者。比较了住院≤8 天和≥12 天的患者的临床特征和治疗药物。
100 例患者中，63 例（63%）住院≤8 天，37 例（37%）住院≥12 天。患有脑血管疾病（29.7%比 11.1%，p=0.019）和腹部手术史（29.7%比 7.9%，p=0.004）的患者更有可能住院≥12 天。住院时间≥12 天的患者 D-二聚体水平[0.78（0.41-1.82）比 0.28（0.16-0.73），p=0.001]和粪便隐血试验阳性率（86.5%比 60.3%，p=0.006）更高。住院≤8 天的患者更常使用益生菌（76.2%比 54.1%，p=0.022）。多因素分析表明，脑血管疾病（比值比[OR] = 4.585；95%置信区间[CI] 1.129-18.624；p=0.033）、腹部手术史（OR = 4.551；95% CI 1.060-19.546；p=0.042）、较高的 D-二聚体水平（OR = 1.928；95% CI 1.024-3.632；p=0.042）和粪便隐血试验阳性率较高（OR = 7.211；95% CI 1.929-26.953；p=0.003）与较长的住院时间相关。
脑血管疾病、腹部手术史、较高的 D-二聚体水平和较高的粪便隐血试验阳性结果是影响轻度缺血性结肠炎患者住院时间的独立且重要的因素。益生菌有助于缩短这些患者的住院时间。
