[Structural changes in the kidneys during experimental infection caused by Yersinia pseudotuberculosis].

A pronounced affinity of Yersinia pseudotuberculosis to the epithelium of renal tubules has been first stated. Microorganisms disseminate through blood into the renal tissue and enter the winding tubule lumen as part of glomerular filtrate. Due to invasion and intensive multiplication of Yersinia pseudotuberculosis within epitheliocytes the epithelium is damaged and necrotic nephrosis develops. Intensive microbial colonization was noted in the tubule lumen. Extra-capillary glomerulonephritis due to Yersinia pseudotuberculosis was detected for the first time. Our data can account for long-term renal disorders in patients with pseudotuberculosis.