Grant D, Stiller C, Duff J, McKenzie N, Wall W, Keown P, Ghent C, Kostuk W, Kutt J, Chin J
CMAJ. 1986 Aug 1;135(3):197-203.
Organ transplantation has become the treatment of choice for selected patients with end-stage failure of the heart, liver or kidneys. The expanding role for organ transplantation, however, has led to a corresponding increase in the complexity of patient management. In response to these changes, University Hospital, London, Ont., has established an interdisciplinary multi-organ transplant service (MOTS). MOTS coordinates donor organ procurement and patient management. Donor organs have been retrieved from as far south as Dalton, Georgia, as far west as Calgary and as far east as Halifax. As of Dec. 31, 1985, 485 transplants had been performed, including 387 kidney transplants, 51 heart transplants, 3 heart/lung transplants, 43 liver transplants (in adults and children) and 1 pancreas transplant. With current immunosuppressive protocols MOTS projects 1-year patient survival rates of 95% after kidney transplantation, 88% after heart transplantation and 81% after liver transplantation. Patient rehabilitation has been excellent.
器官移植已成为特定的终末期心脏、肝脏或肾脏衰竭患者的首选治疗方法。然而，器官移植作用的不断扩大导致患者管理的复杂性相应增加。为应对这些变化，安大略省伦敦市的大学医院设立了一个跨学科多器官移植服务机构（MOTS）。MOTS负责协调供体器官的获取和患者管理。供体器官的获取范围南至佐治亚州的道尔顿，西至卡尔加里，东至哈利法克斯。截至1985年12月31日，已进行了485例移植手术，包括387例肾移植、51例心脏移植、3例心肺移植、43例肝移植（成人和儿童）以及1例胰腺移植。根据目前的免疫抑制方案，MOTS预计肾移植后患者1年生存率为95%，心脏移植后为88%，肝移植后为81%。患者康复情况良好。
