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中国福建省农村居民各种心血管疾病住院与体感温度的关系。

Effect of apparent temperature on hospitalization from a spectrum of cardiovascular diseases in rural residents in Fujian, China.

机构信息

Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350122, Fujian Province, China.

School of Public Health, Guangzhou Medical University, Guangzhou, 511436, China.

出版信息

Environ Pollut. 2022 Jun 15;303:119101. doi: 10.1016/j.envpol.2022.119101. Epub 2022 Mar 3.

Abstract

Cardiovascular disease (CVD) is a leading threat to global public health. Although associations between temperature and CVD hospitalization have been suggested for developed countries, limited evidence is available for developing countries or rural residents. Moreover, the effect of apparent temperature (AT) on the spectrum of cause-specific CVDs remains unknown. Based on 2,024,147 CVD hospitalizations for rural residents from eight regions in Fujian Province, China, during 2010-2016, a quasi-Poisson regression with distributed lag non-linear model was fitted to estimate the AT effect on daily CVD hospitalization for each region, and then pooled in a meta-regression that included regional indicators related to rural residents. Stratified analyses were performed according to the cause of hospitalization, sex and age groups. Finally, we calculated the fraction of CVD hospitalizations attributable to AT, as a reflection of the burden associated with AT. The heat effect appeared at lag 0-1 days, with 19% (95% CI, 11-26%) increased risk of CVD hospitalization, which was worse for ischemic heart disease, heart failure, arrhythmias and ischemic stroke. The decreased AT was associated with increase of hemorrhagic stroke at lag 0-28 days. People aged 65 and above suffered more from the heat effect on cardiovascular and cerebrovascular diseases. Regions with a lower gross value of agricultural production, rural residents' per capita net income, number of air conditioners and water heaters were more susceptible. A large number of hospitalizations were attributable to heat for most subcategories. High AT level increased CVD hospitalization, and the subcategories had different susceptibilities. The effects were modified by individual and regional characteristics. These findings have important implications for the development of targeted interventions and for hospital service planning.

摘要

心血管疾病(CVD)是全球公共卫生的主要威胁。虽然发达国家已经提出了温度与 CVD 住院之间的关联,但发展中国家或农村居民的相关证据有限。此外,大气温度(AT)对特定病因 CVD 谱的影响尚不清楚。基于 2010 年至 2016 年期间中国福建省 8 个地区农村居民的 2024147 例 CVD 住院数据,采用分布滞后非线性模型的拟泊松回归估计了每个地区每日 CVD 住院与 AT 的关系,并在一个包含与农村居民相关的区域指标的荟萃回归中进行了汇总。根据住院原因、性别和年龄组进行了分层分析。最后,我们计算了归因于 AT 的 CVD 住院比例,以反映与 AT 相关的负担。热效应出现在滞后 0-1 天,CVD 住院风险增加 19%(95%CI,11-26%),缺血性心脏病、心力衰竭、心律失常和缺血性中风的风险更高。滞后 0-28 天的低温与出血性中风的增加有关。65 岁及以上的人群更容易受到心血管和脑血管疾病的热效应影响。农业生产总值、农村居民人均纯收入、空调和热水器数量较低的地区更容易受到影响。大多数亚组的大量住院可归因于高温。高 AT 水平增加了 CVD 住院,且各亚组的易感性不同。这些影响受到个体和区域特征的修饰。这些发现对有针对性的干预措施的制定和医院服务规划具有重要意义。

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