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超声监测下的肝脏冷冻手术:动物模型的长期研究

Ultrasound monitored hepatic cryosurgery: longevity study on an animal model.

作者信息

Gilbert J C, Onik G M, Hoddick W K, Rubinsky B, Ferrell L D

出版信息

Cryobiology. 1986 Jun;23(3):277-85. doi: 10.1016/0011-2240(86)90054-4.

DOI:10.1016/0011-2240(86)90054-4
PMID:3525006
Abstract

Ultrasound imaging has been proposed to monitor the amount of frozen tissue during hepatic cryosurgery of primary and metastatic tumors. In this follow-up study, a cryolesion was produced in an adult pig under ultrasound monitoring. The animal was allowed to recuperate for 3 days before being sacrificed. Pathologic and histologic evaluation showed extremely close correlation with the ultrasound image. The necrotic region was clearly observable in the sonogram after 3 days. Ultrasonography can accurately represent the extent of the cryolesion both during as well as following cryosurgery.

摘要

超声成像已被用于监测原发性和转移性肿瘤肝脏冷冻手术期间冷冻组织的量。在这项随访研究中,在超声监测下对一只成年猪制造了一个冷冻损伤。在处死该动物前,让其恢复3天。病理和组织学评估显示与超声图像高度相关。3天后,在超声图中可清楚观察到坏死区域。超声检查能够在冷冻手术期间以及术后准确显示冷冻损伤的范围。

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