Panghate Atul, Jogani Abhinav D, Panchal Sameer, Desai Jigar, Marathe Nandan, Rathod Rajkumar
Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.
Dept of Orthopaedics, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, 400008, India.
J Orthop. 2022 Feb 17;30:98-102. doi: 10.1016/j.jor.2022.01.009. eCollection 2022 Mar-Apr.
The scarcity of mortality data in our country led to systematic effort with aim of evaluating peri-operative parameters associated with mortality in hip arthroplasties to determine better fixation method and reducing avoidable variables.
MATERIALS & METHODS: 252 consecutive patients (133 males and 119 females; Mean age 58.68 years) operated for hip arthroplasties (cemented & uncemented THR and bipolar hemiarthroplasty) were observed prospectively for 2 years. Heart-rate, O saturation and BP were recorded at specific surgical steps and post-operatively for 48 h. Post-operative Trop-T and 2D Echocardiography were done in all patients and D-Dimer and CTPA in indicated ones. All post-operative deaths were extensively studied.
Majority (63%) were operated for traumatic indications.48% belonged to ASA grade-1, 46% grade-2 and 4% grade-3. There was statistically significant association of diagnosis (traumatic aetiology), ASA grade 2, raised Troponin -T, raised D-dimer and pulmonary embolism with mortality. Mortality rate in our study at post-op 48 h was 5.5%, 30 day- 8% and 1-year mortality rate was 19%. With total of 14 deaths, 8 deaths (57.14%) occurred among 127 cemented arthroplasties and 6 deaths (42.86%) among 125 uncemented arthroplasties.
Selection of implant (cemented or uncemented) made no difference in eventual mortality. Collaborative effort of orthopaedic surgeon, anaesthetist and experts from respective fields in elderly high-risk patient with vigilant post-operative surveillance for minimum 48 h would help in lowering mortality associated with hip arthroplasties.
我国死亡率数据匮乏,因此开展了系统性研究,旨在评估髋关节置换术中与死亡率相关的围手术期参数,以确定更佳的固定方法并减少可避免的变量。
对连续252例行髋关节置换术(骨水泥型和非骨水泥型全髋关节置换术以及双极半髋关节置换术)的患者(133例男性和119例女性;平均年龄58.68岁)进行了为期2年的前瞻性观察。在特定手术步骤及术后48小时记录心率、血氧饱和度和血压。所有患者均进行术后肌钙蛋白T检测和二维超声心动图检查,部分患者进行D-二聚体检测和CTPA检查。对所有术后死亡病例进行了深入研究。
大多数(63%)患者因创伤性指征接受手术。48%属于ASA 1级,46%属于2级,4%属于3级。诊断(创伤性病因)、ASA 2级、肌钙蛋白T升高、D-二聚体升高和肺栓塞与死亡率之间存在统计学显著关联。本研究中术后48小时死亡率为5.5%,30天死亡率为8%,1年死亡率为19%。在总共14例死亡病例中,127例骨水泥型关节置换术中8例死亡(57.14%),125例非骨水泥型关节置换术中6例死亡(42.86%)。
植入物(骨水泥型或非骨水泥型)的选择对最终死亡率并无影响。骨科医生、麻醉师及各领域专家的协作,对老年高危患者进行至少48小时的术后严密监测,将有助于降低髋关节置换术相关的死亡率。