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髋关节置换术中围手术期临床、血清学和放射学参数的评估——一项针对印度队列的前瞻性观察研究。

An evaluation of peri-operative clinical, serological and radiological parameters in hip arthroplasties -a prospective observational study of Indian cohorts.

作者信息

Panghate Atul, Jogani Abhinav D, Panchal Sameer, Desai Jigar, Marathe Nandan, Rathod Rajkumar

机构信息

Seth GS Medical College & KEM Hospital, Mumbai, 400012, India.

Dept of Orthopaedics, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, 400008, India.

出版信息

J Orthop. 2022 Feb 17;30:98-102. doi: 10.1016/j.jor.2022.01.009. eCollection 2022 Mar-Apr.

Abstract

BACKGROUND

The scarcity of mortality data in our country led to systematic effort with aim of evaluating peri-operative parameters associated with mortality in hip arthroplasties to determine better fixation method and reducing avoidable variables.

MATERIALS & METHODS: 252 consecutive patients (133 males and 119 females; Mean age 58.68 years) operated for hip arthroplasties (cemented & uncemented THR and bipolar hemiarthroplasty) were observed prospectively for 2 years. Heart-rate, O saturation and BP were recorded at specific surgical steps and post-operatively for 48 h. Post-operative Trop-T and 2D Echocardiography were done in all patients and D-Dimer and CTPA in indicated ones. All post-operative deaths were extensively studied.

RESULTS

Majority (63%) were operated for traumatic indications.48% belonged to ASA grade-1, 46% grade-2 and 4% grade-3. There was statistically significant association of diagnosis (traumatic aetiology), ASA grade 2, raised Troponin -T, raised D-dimer and pulmonary embolism with mortality. Mortality rate in our study at post-op 48 h was 5.5%, 30 day- 8% and 1-year mortality rate was 19%. With total of 14 deaths, 8 deaths (57.14%) occurred among 127 cemented arthroplasties and 6 deaths (42.86%) among 125 uncemented arthroplasties.

CONCLUSIONS

Selection of implant (cemented or uncemented) made no difference in eventual mortality. Collaborative effort of orthopaedic surgeon, anaesthetist and experts from respective fields in elderly high-risk patient with vigilant post-operative surveillance for minimum 48 h would help in lowering mortality associated with hip arthroplasties.

摘要

背景

我国死亡率数据匮乏,因此开展了系统性研究,旨在评估髋关节置换术中与死亡率相关的围手术期参数,以确定更佳的固定方法并减少可避免的变量。

材料与方法

对连续252例行髋关节置换术(骨水泥型和非骨水泥型全髋关节置换术以及双极半髋关节置换术)的患者(133例男性和119例女性;平均年龄58.68岁)进行了为期2年的前瞻性观察。在特定手术步骤及术后48小时记录心率、血氧饱和度和血压。所有患者均进行术后肌钙蛋白T检测和二维超声心动图检查,部分患者进行D-二聚体检测和CTPA检查。对所有术后死亡病例进行了深入研究。

结果

大多数(63%)患者因创伤性指征接受手术。48%属于ASA 1级,46%属于2级,4%属于3级。诊断(创伤性病因)、ASA 2级、肌钙蛋白T升高、D-二聚体升高和肺栓塞与死亡率之间存在统计学显著关联。本研究中术后48小时死亡率为5.5%,30天死亡率为8%,1年死亡率为19%。在总共14例死亡病例中,127例骨水泥型关节置换术中8例死亡(57.14%),125例非骨水泥型关节置换术中6例死亡(42.86%)。

结论

植入物(骨水泥型或非骨水泥型)的选择对最终死亡率并无影响。骨科医生、麻醉师及各领域专家的协作,对老年高危患者进行至少48小时的术后严密监测,将有助于降低髋关节置换术相关的死亡率。

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