Chen Ling, Qiu Zhihuang, Xu Fan, Chen Xingfeng, Chen Liangwan
Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Fujian Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University, Fuzhou, China.
Front Cardiovasc Med. 2022 Feb 16;9:733253. doi: 10.3389/fcvm.2022.733253. eCollection 2022.
The aim of this study was to establish a nomogram to quantify the risk of postoperative pulmonary venous obstruction (PVO) and to make a scientific decision through the decision curve.
In total, 151 PVO patients with total anomalous pulmonary venous connection (TAPVC) repair in our hospital from December 2008 to December 2015 were involved in this study. A nomogram was generated based on the contribution weights of variables, which were found out by logistic analysis. The optimal clinical decision point was determined by the decision analysis and clinical impact curve, which could assess the net benefit between the nomogram and each independent risk factor for postoperative PVO.
Pulmonary venous obstruction with TAPVC repair was found to be positively and independently correlated with preoperative pulmonary hypertension, surgical methods, and preoperative pulmonary venous stenosis.
The study introduced a novel model to aid in clinical decisions making for the patients with TAPVC individually, which may shed light on the evaluation of PVO risk.
本研究旨在建立一种列线图以量化术后肺静脉梗阻（PVO）的风险，并通过决策曲线做出科学决策。
本研究纳入了2008年12月至2015年12月在我院接受完全性肺静脉异位连接（TAPVC）修复术的151例PVO患者。基于通过逻辑分析找出的变量贡献权重生成列线图。通过决策分析和临床影响曲线确定最佳临床决策点，该曲线可评估列线图与术后PVO的每个独立危险因素之间的净效益。
发现TAPVC修复术后的肺静脉梗阻与术前肺动脉高压、手术方法和术前肺静脉狭窄呈正相关且独立相关。
该研究引入了一种新型模型，以帮助为TAPVC患者进行个体化临床决策，这可能为PVO风险评估提供启示。
