Huupponen R, Pihlajamäki K
Int J Clin Pharmacol Ther Toxicol. 1986 Jul;24(7):374-6.
The effect of an intravenous salbutamol dose (2 micrograms/kg or 8 micrograms/kg) on serum insulin and blood glucose was studied in 8 healthy volunteers after different glucose loads. Administration of glucose significantly increased circulating blood glucose and serum insulin concentrations before the salbutamol injection. The acute insulin releasing capacity of 2 micrograms/kg salbutamol was intensified and its blood glucose elevating effect was diminished by preceding glucose loading. Elevation of salbutamol dose from 2 to 8 micrograms/kg caused a 3.4 fold elevation of insulin secretion and an even more pronounced increase in blood glucose response.
在8名健康志愿者身上，研究了不同葡萄糖负荷后静脉注射沙丁胺醇剂量（2微克/千克或8微克/千克）对血清胰岛素和血糖的影响。在注射沙丁胺醇之前，给予葡萄糖显著增加了循环血糖和血清胰岛素浓度。预先给予葡萄糖负荷会增强2微克/千克沙丁胺醇的急性胰岛素释放能力，并减弱其血糖升高作用。将沙丁胺醇剂量从2微克/千克提高到8微克/千克，导致胰岛素分泌增加3.4倍，血糖反应增加更为明显。
