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机器人与手助腹腔镜活体供肾切除术:两种微创技术在肾移植中的比较。

Robotic versus hand-assisted laparoscopic living donor nephrectomy: comparison of two minimally invasive techniques in kidney transplantation.

机构信息

Geneva-Lausanne Transplant Center (Centre Universitaire Romand de Transplantation), Hôpitaux Universitaires de Genève, Rue Gabrielle-Perret-Gentil 4, 1205, Genève, Switzerland.

Division of Urologic Surgery, Geneva University Hospital, Genève, Switzerland.

出版信息

J Robot Surg. 2022 Dec;16(6):1471-1481. doi: 10.1007/s11701-022-01393-x. Epub 2022 Mar 7.

Abstract

Robot-assisted donor nephrectomy (RDN) is increasingly used due to its advantages such as its precision and reduced learning curve when compared to laparoscopic techniques. Concerns remain among surgeons regarding possible longer warm ischemia time. This study aimed to compare patients undergoing robotic living donor nephrectomy to the more frequently used hand-assisted laparoscopic nephrectomy (HLDN) technique, focusing on warm ischemia time, total operative time, learning curve, hospital length of stay, donor renal function and post-operative complications. Retrospective study comparing RDN to HLDN in a collaborative transplant network. 176 patients were included, 72 in RDN and 104 in HLDN. Left-sided nephrectomy was favored in RDN (82% vs 52%, p < 0.01). Operative time was longer in RDN (287 vs 160 min; p < 0.01), while warm ischemia time was similar (221 vs 213 secs, p = 0.446). The hospital stay was shorter in RDN (3.9 vs 5.7 days, p < 0.01).Concerning renal function, a slightpersistent increase of 7% of the creatinine ratio was observed in the RDN compared to the HLDN group (1.56 vs 1.44 at 1-month checkup, p < 0.01). The results show that RDN appears safe and efficient in comparison to the gold-standard HLDN technique. Warm ischemia time was similar for both techniques, whereas RDN operative time was longer. Patients undergoing RDN had a shorter hospital stay, this being possibly mitigated by differences in center release criteria. Donor renal function needs to be assessed on a longer-term basis for both techniques.

摘要

机器人辅助供体肾切除术(RDN)由于其具有与腹腔镜技术相比的精确性和降低的学习曲线等优势,因此越来越多地被使用。外科医生仍然对可能较长的热缺血时间感到担忧。本研究旨在比较接受机器人活体供肾切除术的患者与更常用的手辅助腹腔镜肾切除术(HLDN)技术,重点比较热缺血时间、总手术时间、学习曲线、住院时间、供肾功能和术后并发症。这是一项在协作移植网络中比较 RDN 和 HLDN 的回顾性研究。共纳入 176 例患者,其中 72 例接受 RDN,104 例接受 HLDN。RDN 中更倾向于进行左侧肾切除术(82%比 52%,p<0.01)。RDN 的手术时间更长(287 比 160 分钟;p<0.01),而热缺血时间相似(221 比 213 秒,p=0.446)。RDN 的住院时间更短(3.9 比 5.7 天,p<0.01)。关于肾功能,与 HLDN 组相比,RDN 组肌酐比值略有持续升高(1 个月检查时为 1.56 比 1.44,p<0.01)。结果表明,与金标准 HLDN 技术相比,RDN 安全有效。两种技术的热缺血时间相似,而 RDN 的手术时间较长。接受 RDN 的患者住院时间较短,这可能是由于中心释放标准的差异所致。需要对两种技术的供肾功能进行更长期的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f33f/9606056/c7b8607c7a14/11701_2022_1393_Fig1_HTML.jpg

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